Joan Barau (@JBarau) header
Joan Barau (@JBarau) profile picture

Transposable elements, molecular biology & evolution. Alumni @unicampoficial, former @DeborahBourchis team, now research group leader @imbmainz.

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Joined November 2009
Photo by Joan Barau (@JBarau)Photo by Joan Barau (@JBarau)Photo by Joan Barau (@JBarau)Photo by Joan Barau (@JBarau)Photo by Joan Barau (@JBarau)Photo by Joan Barau (@JBarau)Photo by Joan Barau (@JBarau)Photo by Joan Barau (@JBarau)Photo by Joan Barau (@JBarau)Photo by Joan Barau (@JBarau)
It’s my pleasure to share that our latest manuscript is out now in Nature Biotechnology. This has been an incredibly exciting project! We describe BreakTag, an NGS-based tool for the rapid characterization of CRISPR nucleases and off-target activity. nature.com/articles/s41587-0…
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Congratulations @CristinaPolica4, @hackettlab and team! And a giant thank you for making the MS (and tools) available to the community through @biorxivpreprint. Had we waited for peer review to see this, parts of our work would’ve been delayed by more than a year!
How do chromatin modifications quantitatively impact gene expression? How do sequence variants or combinatorial marks influence relationships? We developed a modular #EpigenomeEditing toolkit to systematically test these Q, published today 🧵… nature.com/articles/s41588-0…
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One of the most memorable moments of my PhD was meeting @HarmitMalik. We had the best time organizing this event together with @JessicaLeismann. And the talk was definitely a blast🧨💣 Thank you all for being there, and thank you, @HarmitMalik, for visiting us! @imbmainz
Yesterday we had a BOMBastic Seminar and Mentoring Session with @HarmitMalik. Thank you so much for visiting US in Mainz! Happy to had the chance of organizing this together with @StelaKanta ☺️
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We had a blast! Proud and thankful for @JessicaLeismann & @StelaKanta for organizing it around the defusal of a 500kg bomb from WW2 just around the corner of the institute. Big thanks to @HarmitMalik for all science, advice and unfazed charisma despite the potentially 🧨 outcome
Yesterday we had a BOMBastic Seminar and Mentoring Session with @HarmitMalik. Thank you so much for visiting US in Mainz! Happy to had the chance of organizing this together with @StelaKanta ☺️
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Yesterday we had a BOMBastic Seminar and Mentoring Session with @HarmitMalik. Thank you so much for visiting US in Mainz! Happy to had the chance of organizing this together with @StelaKanta ☺️
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Can toddlers fake “the sweetspot”?!?! “the sweetspot” = too sick for daycare, too healthy to be quiet at home, a.k.a. feverish running nose. 😂
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Postdoc advertised in my lab to study mobile DNA in mammalian genomes. Permanent position with superannuation and tax concessions in addition to advertised salary. Would suit someone straight out of PhD or a more experienced staff scientist. Please RT nature.com/naturecareers/job…
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We are excited share our latest work! We designed a viral gene against HSV-1 and showed that it spread efficiently during infection in mice
Viral gene drive spread during herpes simplex virus 1 infection in mice biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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#JobAlert #postdoc We are looking for a postdoc to join our team! #sequencing #imaging #nakedmolerat #oocyte #ovary If interested, get in touch (message or email)
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TEs ⚔️ ZFPs Transposons & zinc finger proteins are battling across the animal universe! The battle is particularly fierce in 🦑🐙 and 🐠🐟 with armies of up to 3,000 ZFPs! Psyched about this work led by super talented @JN_Wells who is on the job market! 🎣 Don’t miss him!
Happy to finally share the peer-reviewed version of this work! In case you missed it on biorxiv, read on to learn about a battle between zinc fingers and transposable elements, playing out across 750 million years of animal evolution... genome.cshlp.org/content/33/…
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We are recruiting‼️More info ⬇️⬇️⬇️ – at Naples, Campania
Our team is going to answer your questions about our PhD program on 2 October! We have 35 fully-funded positions in this call. Pass on or share with your colleagues! Sign up here ow.ly/PYQn50PP5sb @IMPvienna @IMBA_Vienna @gmivienna @MaxPerutzLabs @univienna @MedUni_Wien
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Also another great opportunity to have a front seat watching this unfold!!! Congratulations @n_podvalnaya @KettingLab @TheBrainOfPinky!!!!
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On that note, if you're looking for a PhD position and are curious to discover more about SOA, we are recruiting a PhD student to explore the exact mechanism of how SOA brings about hyperactivation of X-linked genes. Apply until November 8th! nitter.cf/imbmainz/status/170486…
The winter call of the IPP is open! Are you excited about #AgeingResearch or can’t get enough of #GenomeStability, #RNABiology & #Bioinformatics? The International #PhDprogramme is offering over 25 projects in groups at IMB, @UnimedizinMainz & @uni_mainz ➡️imb.de/phd
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The day has come when I can finally introduce my new favorite gene to everyone! Everyone, this is SOA. SOA's favorite spot is the X chromosome, so it should feel right at home here on X (formerly known as Twitter)🧬 Read the full article here: nature.com/articles/s41586-0…
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How to assemble and use a thesis committee: docs.google.com/document/d/1… Added to Tools for Science: docs.google.com/document/d/1…
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CUT&RUN of a 3xFLAG tagged protein using 3XFLAG tagged pA-MN. Will the much more abundant triple FLAG sticking out of the pA-MN “elute” the primary anti-FLAG used for the targeting? Someone please say it works and I don’t have to reclone/express/purify a tag less enzyme.😬😬😬😬
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