Biologist and virologist at the @fredhutch. He/him. 🇫🇷
Seattle, USA
Joined December 2010
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marius walter retweeted
Proof-of-concept work led by @_mariusW and published in @naturecomms raises hope that ‘gene drive’ could one day form basis of curative #genetherapy for #herpes.
bit.ly/4eVhfwV
marius walter retweeted
Proof-of-concept work led by @_mariusW and published in @naturecomms raises hope that ‘gene drive’ could one day form basis of curative #genetherapy for #herpes.
bit.ly/4eVhfwV
marius walter retweeted
Very proud that our paper “Viral gene drive spread during herpes simplex virus 1 infection in mice” made Editor’s Highlights @NatureComms – under Microbiology and Infectious Diseases. Congrats to first author @_mariusW! nature.com/ncomms/editorshig…
The final version of our work is published!
We developped a viral gene drive against HSV-1 and showed that it spread efficiently during infection in mice
nature.com/articles/s41467-0…
marius walter retweeted
🚨New Review🚨 There's a long history of evidence for DNAme antagonism of CTCF in mammals. How important is it in normal dev. or disease contexts? @DaanNoordermeer @AnaMonteagudo4 and I put together a summary in this collaborative review @NatureSMB (1/4) rdcu.be/dBDFD
marius walter retweeted
Happy to share our last work: "Alternative silencing states of Transposable Elements in Arabidopsis" biorxiv.org/content/10.1101/…
marius walter retweeted
A deadly viral illness is exploding in West Africa. Researchers are scrambling to figure out why
#lassa #Virus
science.org/content/article/…
marius walter retweeted
A viral gene drive has been successfully tested in animals for the first time
A viral gene drive is a piece of DNA that can copy and paste itself into other viruses with the help of #CRISPR, until eventually all viruses carry the gene drive
newscientist.com/article/240…
marius walter retweeted
Why not gene drive in viruses? @_mariusW made it happen, and @ScienceMagazine is on the scent. So rad (from @sciencecohen) | Fighting viruses with viruses? ‘Gene drive’ offers new strategy to beat infections science.org/content/article/…
We are excited share our latest work! We designed a viral gene against HSV-1 and showed that it spread efficiently during infection in mice
Viral gene drive spread during herpes simplex virus 1 infection in mice biorxiv.org/cgi/content/shor… #biorxiv_micrbio
A viral gene drive spread by the co-infection of cells by wildtype and engineered viruses. Our latest results shows that co-infection and recombination occurs at a high frequency in vivo during HSV-1 infection. I hope all (reviewers) that didn’t believe it would will take notice!
The work was a team effort between the group of @EricVerdin at the @BuckInstitute and the group of Keith Jerome @fredhutch
marius walter retweeted
France and Italy have been under-investing in basic research for years. And it shows.
Number of 2023 #ERC consolidator grants vs. GDP of countries?
Here I show # ERC grants by country, their GDP and # ERCs/GDP.
Germany, UK, and Spain are on par
The Netherlands, Denmark, Austria, Israel, and Belgium over-perform
France, Italy, Norway, and Poland under-perform
Glad that I could contribute to this nice story by @TimoninaDaria
Contributed by @TimoninaDaria @ Judith Campisi @_mariusW @EricVerdin et al. Congratulations 👏👏
biorxiv.org/content/10.1101/…
marius walter retweeted
#preprint now online: Human herpesvirus 6B (HHV-6B) detection and genome-wide host expression profiles implicate HHV-6B as a pulmonary pathogen after hematopoietic cell transplantation researchsquare.com/article/r… @fredhutch @PergamIC @ErikaKampouri @roychemaly @MichaelGIsonMD
marius walter retweeted
The Webb telescope has detected carbon dioxide and methane in the atmosphere of exoplanet K2-18 b, a potentially habitable world over 8 times bigger than Earth. Webb’s data suggests the planet might be covered in ocean, with a hydrogen-rich atmosphere: go.nasa.gov/3sGKNLe
ALT A graphic titled “Exoplanet K2-18 b: Atmosphere Composition.” The graphic shows the spectra of the exoplanet K2-18 b from NIRISS and NIRSpec in the form of a graph, with the vertical y-axis labeled as Amount of Light Blocked and the horizontal axis labeled as Wavelength of Light (microns). The data is plotted as dots with vertical error bars. A jagged blue line running through the plot represents the best-fit model. There are semi-transparent magenta, red and green vertical columns also scattered across the plot, indicating where variations in the line represent the presence of methane, carbon dioxide, and dimethyl sulfide (combined with other molecules), respectively. Behind the graph is an illustration of the planet and star. The planet is a large fuzzy blue-ish sphere off to the right, taking up half of the background. The red star is smaller at the bottom left of the entire graphic.
marius walter retweeted
Very excited to share the latest preprint from the Lithgow Lab @BuckInstitute linking protein insolubility with Alzheimer's and the diseases of aging!
biorxiv.org/content/10.1101/…
A thread of the story (1/11)