Computational Medicine
London, England
Joined February 2011
- Tweets57
- Following124
- Followers77
- Likes128
New paper out in Nature Communications: structural variation in the Qatari population. Great team effort with @kfakhro and @elbayaliyev.
#genomics #structuralvariation
doi.org/10.1038/s41467-025-6…
Mario Falchi retweeted
Massive news: eLife to abolish accept/reject decisions: papers will just be “peer reviewed”. Others can argue about this, but lots of interesting consequences. 1/9 elifesciences.org/articles/8…
Mario Falchi retweeted
#Ukraine please RT: phone operator @VodafoneUK, do not cut me out from my relatives and friends. Three days of heartless lies already! I can pay for my calls to #Ukraine +380! No need for free calls, which are dropped, before they go through
please RT: UK mobile operators declared, calls from #UK to #Ukraine for FREE until March 25. @VodafoneUK informs me and DROPS all my calls to +380 numbers 💙💛 from today, while misinforming, it must be on the side of #Ukraine. A heartless business move
Mario Falchi retweeted
Our paper on #COVID19 related loss of smell and taste is now published: nature.com/articles/s41588-0…
Mario Falchi retweeted
A remarkable moment in the history of GWAS!
"... using GWAS data from 5.4 million individuals of diverse ancestries, that 12,111 independent SNPs that are significantly associated with height account for nearly all of the common SNP-based heritability."
biorxiv.org/content/10.1101/…
Mario Falchi retweeted
We have submitted new results to medRxiv:
Omicron infection enhances neutralizing immunity against the Delta variant
The preprint can be found here:
sigallab.net/
Mario Falchi retweeted
Want to learn about GWAS, its QC, analysis tools, imputation, meta-analysis, PRS and MR? Apply for our 7th edition of online LIVE 5-day course “Intro to statistical analysis of GWAS”! @UniOfSurrey with support from @eshgsociety tinyurl.com/2p8wurv6 Please, RT
Mario Falchi retweeted
We conducted a transcriptomic survey to study properties of escape from X-inactivation across tissues and cells in female twins. @A_L_Roberts @_alesssia @Julia_Moustafa @MarioFalchi @kerrin_small @TwinsUKres
biorxiv.org/content/10.1101/…
Mario Falchi retweeted
Research | Ana Valdes & Patrick Wyatt (@TwinsUKres, @NottmBRC) find that the postprandial glycaemic dip is a predictor of hunger and subsequent food intake.
nature.com/articles/s42255-0…
Mario Falchi retweeted
Here is the full sequence of the Pfizer vaccine, courtesy of the WHO. 4284 nucleotide, 1273 amino acids. All U are 1-methyl-3'-pseudouridine. PolyA has strange structure, is broken up with GCAUAUGACU.
Mario Falchi retweeted
Now also out in the print edition: Nature Reviews Genetics volume 22, pages19–37(2021)
nitter.cf/NatureRevGenet/status/…
Genetics meets proteomics: perspectives for large population-based studies go.nature.com/2QOTCMO #Review by @ksuhre, @markmccarthyoxf & @jochwenk @scilifelab @KTHresearch @WeillCornell @HumanGeneticsOx #humanproteome #pQTLs
Mario Falchi retweeted
I’ve literally treated many dozens of people who developed diabetes during #COVID19 from drinking coke. It’s their products that are filling up our emergency rooms
Great marketing ploy by Coca-Cola to dedicate bottles of the drink that causes so much illness and extra Covid deaths globally to the teachers and caregivers that have to clean up the mess... foodpolitics.com/2020/12/foo…
Mario Falchi retweeted
We are hiring! Check out the position below if you are interested in using bioinformatics to develop novel drugs for autoimmune diseases
novartis.com/careers/career-…
Mario Falchi retweeted
Using large-scale #GWAS, we screened 955 circulating proteins for their role in #COVID19 outcomes using #MendelianRandomization.
We found that increased OAS1 levels strongly protected against COVID19 outcomes.
1/n
medrxiv.org/content/10.1101/…
Mario Falchi retweeted
Our preprint on covid antibodies out today
Estimates of the Rate of Infection & Asymptomatic #COVID19 Disease in a Population Sample from SE England
👉 Seroprevalence = 12%
👉 Anosmia = highest symptom specificity for #SARSCoV2 antibody response
Link: medrxiv.org/content/10.1101/…
@KingsCollegeLon @Join_ZOE #IDTwitter
Mario Falchi retweeted
Thanks to our 4 million app users reporting skin symptoms we added this to our list and now know that in 8 percent of people it is a key and early sign of Covid that everyone needs to know about @KingsCollegeLon @Join_ZOE thesun.co.uk/news/12117557/s…
Diagnostic value of skin manifestation of SARS-CoV-2 infection medrxiv.org/cgi/content/shor… #medRxiv
Mario Falchi retweeted
Here is a new paper from the Regeneron Genetics Center biorxiv.org/content/10.1101/… A new, fast ML method for whole genome regression. The REGENIE website is here rgcgithub.github.io/regenie/ with free source code. Amazing work from @jojoladisco @lelandbarnard @EvanKMaxwell 1/10
Mario Falchi retweeted
Our interactive map of Symptomatic #covid19 bit.ly/symptomaticCovid19 made with @Join_ZOE @KingsCollegeLon #covidradar
improvement of myopia prediction - AUC 0.75 - great paper from Pirro and Chris @KingsCollegeLon
nature.com/articles/s41588-0…