Robert McGinty (@McGintyLab) profile picture

Robert McGinty

@McGintyLab

Assistant Professor in Division of Chemical Biology and Medicinal Chemistry @UNCPharmacy

Joined December 2016
  • Tweets14
  • Following13
  • Followers172
Robert McGinty retweeted
Rebecca Berlow (@BerlowLab) profile picture
Rebecca Berlow@BerlowLab13 Sep 2023
Calling all NC biophysicists! We are pleased to host the Carolina Biophysics Symposium on the beautiful UNC Chapel Hill campus on November 9-10. Registration is now open! See details about the symposium here: cbs.web.unc.edu Please RT to help spread the word!
Image from Rebecca Berlow (@BerlowLab)
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I have some exciting news to share with you today 😊
UNC Pharmacy (@UNCPharmacy) profile pictureUNC Pharmacy@UNCPharmacy25 Aug 2023
Please join us in congratulating #UNCPharmacy's Aleksandra Skrajna, a postdoc in the McGinty Lab, for receiving a 2023 Postdoctoral Award for Research Excellence (PARE). This award recognizes research promise demonstrated by individual postdoctoral scholars!
Image from UNC Pharmacy (@UNCPharmacy)
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Robert McGinty retweeted
cryoEM Papers (@cryoEM_Papers) profile picture
cryoEM Papers@cryoEM_Papers8 Mar 2023
Lipid nanodiscs as a template for high-resolution cryo-EM structures of peripheral membrane proteins biorxiv.org/cgi/content/shor…
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The Penn State Center for Eukaryotic Gene Regulation (CEGR) is hosting our 39th Summer Symposium on gene regulation and chromatin biology from August 6-9, 2023 at our University Park campus. Registration is open NOW: symposium.psu.edu.
Image from Center for Eukaryotic Gene Regulation at PSU (@cegrPSU)
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Congratulations to Cathy Spangler PhD for receiving the Dean's Distinguished Dissertation Award! #TargetedTheraputics #Leukemia @McGintyLab
UNC Graduate School (@UNC_GradSchool) profile pictureUNC Graduate School@UNC_GradSchool16 Mar 2023
Delighted to announce this year's Dean's Distinguished Dissertation Award recipients: Jocelyn Burney @reliunc with the @unccollege; Cathy Spangler with @UNC_BCBP; Qiang Zhang with @jointbme; and Julie Kafka with @UNCpublichealth ow.ly/7OqF50Nk2pY #UNCGradStudents
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I would like to share with you our new work on the identification of the first bona fide 'reader' of #histone H3K79 methylation, which has been a mystery since the discovery of this modification in 2002. science.org/doi/10.1126/scie… today online in @ScienceMagazine
Menin “reads” H3K79me2 mark in a nucleosomal context

Menin “reads” H3K79me2 mark in a nucleosomal context

A nucleosome-based photoaffinity probe identified menin as an H3K79me2 reader that binds enhancers to activate transcription.

science.org
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Congrats to team lead by @catler4ohsu and @a_skrajna on their tour de force in chromatin structural biology published today in @nchembio. Really proud to add that the first 9 authors on this paper are women! nature.com/articles/s41589-0…
Structural basis of paralog-specific KDM2A/B nucleosome recognition

Structural basis of paralog-specific KDM2A/B nucleosome recognition

Nature Chemical Biology - Spangler et al. used a substrate inhibitor covalent conjugate strategy to solve cryo-EM structures of nucleosomes in complex with the lysine demethylase KDM2, which...

nature.com
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Work from Robert McGinty & colleagues solved cryo-EM structures of nucleosomes in complex with lysine demethylase KDM2, revealing that KDM2A anchors to the acidic patch to direct histone H3K36-specific demethylation. Free to read: rdcu.be/c5MAP nature.com/articles/s41589-0…
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Robert McGinty retweeted
Cathy Spangler (@catler4ohsu) profile picture
Cathy Spangler@catler4ohsu16 Feb 2023
Final project from my graduate work is published today! Awesome collaborative work between so many lab members, including @a_skrajna, @gabbygrowsxtals, and @nate_wesley3! nature.com/articles/s41589-0…
Structural basis of paralog-specific KDM2A/B nucleosome recognition

Structural basis of paralog-specific KDM2A/B nucleosome recognition

Nature Chemical Biology - Spangler et al. used a substrate inhibitor covalent conjugate strategy to solve cryo-EM structures of nucleosomes in complex with the lysine demethylase KDM2, which...

nature.com
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UNC has an faculty search open in Biophysics
Qi Zhang Lab (@QiZhangLab) profile pictureQi Zhang Lab@QiZhangLab25 Nov 2020
Our department is hiring! Open rank tenure/tenure-track faculty position in Molecular and Cellular Biophysics. The priority deadline for application is January 6, 2021. Please visit the following UNC-Chapel Hill website for details. unc.peopleadmin.com/postings…
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Seems I was late to the party - Congrats to @JoshBoyerPhD @catson4unc @JoshuaStrauss5 on their paper showing how chromatin binding inactivates cGAS! A fun collaboration with @QiZhangLab science.sciencemag.org/conte…
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MORE PAPERS!!!🤯🤯🤯🤯🤯 Self-recognition: cGAS inhibited by Chromatin binding science.sciencemag.org/conte… science.sciencemag.org/conte…
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Really proud of our collaborative effort to decipher the nucleosome interactome led by @a_skrajna academic.oup.com/nar/advance…
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