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Official Twitter account of the Klenerman lab (not Paul himself). We work on CD161++/MAIT cell biology, HCV & SARS-CoV-2 immune defence, and memory inflation.

Joined September 2021
Photo by PaulKlenermanLab (@PKlenermanLab)Photo by PaulKlenermanLab (@PKlenermanLab)Photo by PaulKlenermanLab (@PKlenermanLab)
Pressure to publish jumps. And researchers have no time to do science. (New survey from Elsevier) Survey of 3200 researchers: 1. Only 45% of scientists have sufficient time for actual research. 2. For 68%, the pressure to publish today is greater than 2-3 years ago. 3. 29% of researchers are considering relocating to another country (for better funding, work‐life balance, or greater research freedom). 4. 58% of researchers use AI tools in their work. 5. Reported benefits from AI: saving time (58%), helping with literature summaries (61%), literature reviews (51%), data analysis (38%), drafting proposals (41%), and drafting papers (38%). Globally, life in academia is getting worse. For students & postdocs - it’s especially hard to decide on an academic career. ❗️ A few days ago, I gave a lecture on this topic. “PhD: Dreams, Reality and Consequences” Watch it here: lnkd.in/dA_GhYwd (I’ll appreciate if you ‘like’ this video - you will GREATLY help it reach more students.)
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A new study finds that extended intervals between #SARSCoV2 mRNA vaccine doses lead to higher quality T cell responses and lower inflammation after vaccination in humans. Learn more in @SciImmunology: scim.ag/3HTbCnm
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PaulKlenermanLab retweeted
Very happy to share the latest work out in @SciImmunology. Here we use single cell RNA-sequencing in combination with an activation induced marker (AIM) assay to explore the impact of the COVID-19 vaccine regimen on T cell quality. With @PKlenermanLab @nprovine @NDMOxford
A new study finds that extended intervals between #SARSCoV2 mRNA vaccine doses lead to higher quality T cell responses and lower inflammation after vaccination in humans. Learn more in @SciImmunology: scim.ag/3HTbCnm
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PaulKlenermanLab retweeted
MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines science.org/doi/10.1126/scii… @SciImmunology @PKlenermanLab @aliamini419 @TheLucyGarner @nprovine 🇬🇧
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PaulKlenermanLab retweeted
Dosing interval is a major factor determining the quality of T cells induced by SARS-CoV-2 mRNA and adenoviral vector vaccines @SciImmunology @PKlenermanLab @nprovine 🇬🇧 science.org/doi/10.1126/scii…
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PaulKlenermanLab retweeted
It was a delight to contribute to the @EASLedu Basic Science School @TGU_Oxford & deliver the state-of-the-art lecture. Thanks to all faculty (@TamCarg @EmmaCulver6 @PKlenermanLab @EleanorBarnesOx) & EASL. Happy to collaborate for work on FNA's! @blizard_inst @BartsHepatology
It was an honour to host the @EASLedu Basic Science School at the TGLU Oxford @TGU_Oxford @NDMOxford with a brilliant keynote from @druppygill and lots of hands on learning in the lab. Great to connect with delegates from across the world @DavidTrampert @DraMartaAlonsoP
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PaulKlenermanLab retweeted
Our upcoming EASL Basic Science School will introduce you to advanced immunological techniques as applied to translational hepatology research. These experimental hands-on sessions will be led by organisers @EleanorBarnesOx, Paul Klenerman, @EmmaCulver6, @TamCarg, @tom_marjot, and @RoryPeters16. Apply by 30 September: easl.eu/event/basic-science-… #LiverTwitter @PKlenermanLab
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PaulKlenermanLab retweeted
@PKlenermanLab indoctrination worked a charm! Need a solid petition now to get this over the line.
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PaulKlenermanLab retweeted
On Thursday 25th April, we celebrated the kind donation of Sir Peter Medawar’s Nobel Prize medal, to inspire good science at Oxford: immunology.ox.ac.uk/news/unv… @OxfordBiology @Dunn_School @NDMOxford @OxfordMedSci @PKlenermanLab @fgissa @NDSurgicalSci
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PaulKlenermanLab retweeted
Some people on the @Bioconductor forum are really rude when answering questions. If you don't want to help, maybe just don't respond, rather than treating people like they are idiots! #Bioinformatics #academia
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PaulKlenermanLab retweeted
Inspiring and thought-provoking session with @PKlenermanLab and @ZakiyaLeeming from @rncmlive at @sim_manchester to launch the science strand of our #T4TM project. More information on the project here: immunology.ox.ac.uk/about/pu… – at North West, England
Our science workshop for the Thanks for the Memories project has kicked off! #T4TM @CoopAcademies students are working with @RNCMPRiSM and @UniofOxford to compose music inspired by immunology. Welcoming students from @WalkdenCoop @coopfailsworth @CoopAcademyNM @CoopManchester
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📣Just 1 week left to submit your abstract for the @BSI_Oxford & @OxImmuno symposium #OIS24 will showcase diverse disciplines & technologies incl. fundamental #biology, #infection & imaging, systems #immunology, therapeutics & #AI 👏 Submit by Mon 5 Feb🔗bit.ly/46W0rkq
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PaulKlenermanLab retweeted
MIT University released free online courses. No textbooks or fees required. Here are 10 courses you don't want to miss:
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Next speaker: the Sidney Truelove professor of Gastroenterology @PKlenermanLab, with "A tale of two papers" - and stories about vaccine research and liver resident cells that increased our understanding of defences for liver infection
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PaulKlenermanLab retweeted
Has anyone tested different RNase inhibitors with the 10x Genomics multiome protocol? The recommended Protector RNase Inhibitor from Merck is currently backordered. #scRNAseq @10xGenomics
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