Post-doc @BoultonLab @TheCrick | @TheCesareLab & @PutoczkiLab alumni | Cancer biologist with interest in pancreatic cancer | Views = my own.
Joined September 2013
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1/ Delighted to share my first first-author paper from my PhD @PutoczkiLab @WEHI_research 🎉 Starting from the simple observation of different organoid morphologies present in the culture, then I just kept going down the rabbit hole. 🐰 nature.com/articles/s41418-0…
Ronnie Ren Jie Low retweeted
1/Today in @NatureComms
“A CPC-shelterin-BTR axis regulates mitotic telomere deprotection”.
Here we identify the mechanism that unwinds telomere-loops (t-loops) during mitotic arrest to activate the DNA damage response and signal mitotic stress.
nature.com/articles/s41467-0….
Ronnie Ren Jie Low retweeted
It's out! We report 3D mapping of human pancreatic precancer and associated genetic alterations. With the brilliant @AshleyKiemen and @deniswirtz . Tweetorial to follow soon. nature.com/articles/s41586-0…
Ronnie Ren Jie Low retweeted
We have great news - our postdocs @MartinaPeritore and @RRJLow have been awarded #MSCA postdoctoral fellowships!! Congratulations 🥳🙌🏾👩🏾🔬👨🏾🔬 Looking forward to the exciting science to come!
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Ronnie Ren Jie Low retweeted
1/ A pre-print detailing the most recent effort from our long-standing collaboration with the @makotothayashi2 lab is now live: "A CPC-shelterin-BTR axis regulates mitotic telomere deprotection". biorxiv.org/content/10.1101/…
Ronnie Ren Jie Low retweeted
Take a peek at my cover art accepted for the 21 Dec issue of @CellChemBiol! Gratitude to @AIRC_it for supporting my research and shout-out to fellow authors @hildaApickett, @sadimaro80, and Alex Sobinoff. #drugdiscovery #CancerResearch
Ronnie Ren Jie Low retweeted
Chemotherapy basics to know. If you know anyone going through cancer care, please check in with them today.
from @CellCellPress
Happy to contribute to this project led by @scoscona and Hilda Pickett when I was @TheCesareLab . Congrats to the first authors, Alex and @sadimaro80 to bring this work to light.
Our latest paper in @CellChemBiol unveils APOD53, an antiproliferative cyclic peptide co-discovered with @PicketHilda and @TheCesareLab to bind TRF2. Kudos to first authors @sadimaro80 and Alex Sobinoff! Special thanks to @AIRC_it for their support. authors.elsevier.com/c/1iDJY…
Ronnie Ren Jie Low retweeted
1. ENTER #mRNAvaccines for #pancreaticcancer! Long-term #PDAC survivor story PART3.
"Do #PDACs REALLY have vaccine neoantigens (NAs)"? (aren’t they lowly mutated?)
If each patient = own NAs, how do you vaccinate?
Maybe mRNA? But how?
@Nature nature.com/articles/s41586-0…
👇🏽 [1/32]
Ronnie Ren Jie Low retweeted
Our #OpenAccess review on #PancreaticCancer - advances & challenges is now online at @CellCellPress
Many thanks to @CJHPhD @Pasca_Lab & @LyssiotisLab for all the hard work & @jiaying_tan6 for the opportunity.
It’s FREE to read so share widely!
cell.com/cell/fulltext/S0092…
Ronnie Ren Jie Low retweeted
I am delighted to share our last study on the mechanisms by which EMT tumor cells resist to chemotherapy. Very proud of Maud Debaugnies, the first author ! Thanks also to @JMendez_DNA group which helps us to understand how RHOJ regulates DNA repair.
nature.com/articles/s41586-0…
Ronnie Ren Jie Low retweeted
We are hiring! A postdoc position (Level A) is available to join the Neuroinflammation Laboratory at The Florey Institute, Melbourne. If you own a PhD in tau/ApoE and interested in dementia-causing inflammatory responses, email me your CV! [email protected] @TheFlorey
Ronnie Ren Jie Low retweeted
Led by @RRJLow at @PutoczkiLab, a @WEHI_research team and collaborators used a lineage-traced sporadic model of #PancreaticCancer to study how S100 family proteins are linked to #organoid morphology and EMT in pancreatic cancer.
📎 @cddpress | go.nature.com/3Ys71eo
3/ A shout out to @BenStanger01's paper that has enlightened me when I was working on this project. doi.org/10.1016/j.devcel.201…
4/ Stay tune for more papers from my PhD study with #Pancreaticcancer & #Organoids
Ronnie Ren Jie Low retweeted
We had a great time @GenomeConf. Thank you @BlewittMarnie for organising. Looking forward to 2024!
Ronnie Ren Jie Low retweeted
Our latest results have been published! onl.bz/H2h55Cx In this study, we aimed to explore the function of the RecQ helicase member WRN in mitotic telomere deprotection. Telomere is a protective DNA-protein structure at the end of our chromosomes. (1/4)
I made it to my PhD graduation!👨🎓It was a roller coaster ride (Tracy on maternity leave, COVID lockdown, interesting collaborators and having a sick family member overseas)! Thank you Tracy😊, for being supportive and helped me survive all those stressful times. 😱@PutoczkiLab
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