Asst. Prof. at La Jolla Institute for Immunology. Signaling and Gene Expression. Immunochemical Circuits of Inflammation. https://nitter.cf/t.co/u6A2lxjsCN Hiring!
San Diego, CA
Joined July 2021
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Seeing this reminded me to inform yall we are moving to bluesky
samyers-lab.bsky.social
adiós por ahora
Samuel A Myers retweeted
If you really love your protein of interest commit to a tattoo @ardemp
If all my friends jump....
I hate downloading new apps, but this was a good call. I hope you post your science, good news, and memes on Bluesky soon. Byeeeeee. bsky.app/profile/gottschalkl…
Samuel A Myers retweeted
We are launching our latest product, Arg-C Zero!
This is a really cool protease and it delivers ultimate efficiency, basically close to 0% missed cleavages at arginine residues (hence the "Zero"... get it ? 😅 )
Feel free to reach out for any Q's :)
#Proteomics #TeamMassSpec
🚀Introducing Arg-C Zero (KPL0146)🧬
Next-gen proteomic enzyme with close to 0% missed cleavages at Arginine residues!
🔬100% Arginine cleavage + ultimate specificity = next-level protein analysis magic ✨
🧬 Details: kplbio.com/product/arg-c/ #Proteomics #TeamMassSpec #proteins
Samuel A Myers retweeted
APEX peroxidase is a versatile tool for proximity labeling and electron microscopy (EM) but its requirement for toxic H2O2 is a liability. We now report LaccID, a multicopper oxidase evolved from an ancestral fungal laccase that oxidizes aromatic substrates using non-toxic O2 instead of H2O2. We use LaccID for EM imaging of cultured cells and fly brains, and for proteomic mapping of the changing surface composition of T cells that engage with tumor cells via antigen-specific T cell receptors.
Samuel A Myers retweeted
Nature: What’s your advice for today’s PhD students?
Hopfield: Where two fields are driven apart, see if there is anything interesting in the crack between them.
A few days ago, I spoke with @Nature about my work at the interface between disciplines
nature.com/articles/d41586-0…
Best group costume, 2024 @ljiresearch. After Mario rode on Yoshi and jumped Boo, it was clenched. Happy Halloween!
:)
Excited to share our latest manuscript dedicated to the remarkable Donald F. Hunt, a true pioneer in the field of mass spectrometry and O-GlcNAc research! From Fringe to the Mainstream: How ETD MS brought O-GlcNAc to the masses mcponline.org/article/S1535-…
Samuel A Myers retweeted
Very excited to share that the main paper from the Strengthening Democracy Challenge is out today in @ScienceMagazine! It’s been a long road to get to get to this point.
🧵👇
science.org/doi/10.1126/scie…
Samuel A Myers retweeted
Can a deadly rash be cured by repurposing drugs? Our @Nature paper says yes! Deep Visual Proteomics reveals JAK inhibitors as potential TEN treatment. A game-changer in #dermatology & #SpatialProteomics.
Congratulations to all!
@NordmannThierry's tweetorial explains below:
Published today! Spatial proteomics reveals JAK/STAT as a target for Toxic Epidermal Necrolysis, an often fatal skin reaction to common medication. We validated our findings in pre-clinical models & successfully treated the first patients worldwide.🧵⬇️ nature.com/articles/s41586-0…
Samuel A Myers retweeted
Thrilled to share that "The Ecstasy of Microscopy" has won Best #Documentary Short @RawScienceTV Film Festival. Massive thank you to @LJIMicroCore @ljiresearch for making this film possible. It was a privilege to share the film with an audience of curious minds in New York City.
Samuel A Myers retweeted
Need a power/sample size calculation for a study or upcoming grant? Led by @emil_hs, we built a simple, free, and pain-free (!) shiny app. feedback welcome plz share with interested parties. check it out: powercalc.ca 🦾🤓
@sholzberg @kieranrcampbell @JeffsLianne @aaron_drucker @WallisCJD @NEJMEvidence @JonZipursky @ChanaSacks
Samuel A Myers retweeted
Different signaling interpretations by PKC eta and theta control T cell function and exhaustion biorxiv.org/cgi/content/shor… #biorxiv_immuno
Samuel A Myers retweeted
An exciting advance in Type 1 diabetes
First person to receive her own stem cells, reprogrammed with transcription factors, to reverse it!
@CellCellPress
sciencedirect.com/science/ar…
@Nature
nature.com/articles/d41586-0…
Samuel A Myers retweeted
I’m excited to announce the launch of our company @KPL_ApS , and website: kplbio.com.
The goal is to make some cool proteins, starting with proteases for #proteomics purposes ☺️. First product is the infamous LysC (lys.bio) but stay tuned more!
Love to see it
A huge congratulations to Jesse Velasco who successfully defended his PhD thesis today! As my first graduate student this one is really special. Thank you Jesse! @UofUBiochem
This seems like a well done study. I find it hard to interpret the results if the mutated STY residue has never been described as modified. But still, very cool.
Base editing screen targeting all feasible S/T/Y residues (close to 600.000) to investigate phospho-dependent signaling.
biorxiv.org/content/10.1101/…
Samuel A Myers retweeted
Thrilled to share that my #documentary The Ecstasy of Microscopy is an official selection for the 10th annual Raw Science Film Festival taking place in #NYC This film was a collaboration with
@LJIMicroCore
@ljiresearch
TY #RRSFF2024 fiscal sponsors
@RFS_Science
@NewYorkLiveArts
