Instructor | Research Faculty @ Harvard Medical School
Boston, MA
Joined November 2020
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So excited for getting my first grant as PI! After 2 assessment rounds and the today's final, the Women's Giving Circle voted to fund my project. Many thanks for your support @UACachexia @KevinMurachPhD and Tyrone Washington! Glad to be part of the @UARKHHPR and @uacoehp family! – at Arkansas, USA
Thank you to @JPhysiol for inviting me to present our Editor’s Choice paper! I had the pleasure of presenting, but this was a team effort - thank you @UACachexia @PJKoopmansPhD @KevinMurachPhD and all our collaborators. Exercise may be a powerful tool against cancer cachexia.
Stavroula Tsitkanou (@BIDMChealth) explains her recent findings that #exercise may help protect against cancer-related muscle wasting and could even slow tumour growth 💡🔬
Watch the #PhysiologyShort here!👇️
buff.ly/V0VSMvJ
Read the paper🎓️
buff.ly/LEJcnTe
Excited to see our work selected as an Editor's Choice in @JPhysiol
Grateful to all co-authors, PIs @UACachexia @KevinMurachPhD and @PJKoopmansPhD for this great collaboration!
🎓️ EDITOR'S CHOICE🎓️
In a mouse model of cancer cachexia, Tsitkanou (@UACachexia) et al. show the potential for exercise training not only to mitigate muscle loss, but also to reduce tumour burden.
🔗 buff.ly/UcVWU9k
Stavroula Tsitkanou retweeted
Part 2 of the collaboration with @STsitkanou showing the “PoWeR” of concurrent exercise training with cancer, this time pre-conditioning! @UACachexia @KevinMurachPhD
Exercise training prior to and during cancer in mice preserves muscle mass, reduces tumour weight and suppresses molecular mediators of cachexia
physoc.onlinelibrary.wiley.c…
Stavroula Tsitkanou retweeted
A heavy lift from a literal strongman, PhD candidate @PJKoopmans “The Age-Dependent Resident Myonuclear Multi-Omic Response to a Skeletal Muscle Hypertrophic Stimulus” 💪🏻 biorxiv.org/content/10.1101/…
Stavroula Tsitkanou retweeted
@franmorena98 et al @AReginaCabrea @KevinMurachPhD @PJKoopmans @STsitkanou @m_ruqaiza: Global mitophagy inhibition via #BNIP3 #ablation is not sufficient to alleviate #skeletalmuscle impairments in male and female tumor-bearing mice
ow.ly/2yi850WaRst
Stavroula Tsitkanou retweeted
Our 3rd new manuscript this week: @DelfinisLuca found a mitochondrial-targeted compound partially prevents muscle weakness without preventing atrophy in ovarian cancer. This opens a new direction for therapies targeting muscle ‘quality’. biorxiv.org/content/10.1101/…
Excited for this project being off the press this morning! Our study showed that the mitochondrial antioxidant SkQ1 may attenuate tumor-induced muscle loss in males while improving muscle contractility in tumor-bearing female mice.
Fresh out in @AJPCellPhys and off the presses from lead author @STsitkanou with @Franmorena98 @AReginaCabrera @eleanor_schrems @SeongLim7 @ChrisPerryMito @KevinMurachPhD and more!
journals.physiology.org/doi/…
Stavroula Tsitkanou retweeted
Manuscript Acceptance Dance!
Congrats @STsitkanou @Franmorena98 @AReginaCabrera @KevinMurachPhD @eleanor_schrems @ChrisPerryMito and all other coauthors!
Watch for Roula's outstanding work in @AJPCellPhys soon!
So glad for this study being published online this morning.
What's the role of exercise in ALS?Exercise training at a symptomatic stage does NOT induce any adverse effect in a TDP-43 mouse model characterized by an ALS-remiscent aggressive disease.
journals.physiology.org/doi/…
Stavroula Tsitkanou retweeted
Fully-funded PhD position in my lab. Spread it around. Email me if you’re interested! #myotwitter
So glad for this work!
Biological sex divergence in transcriptomic profiles during the onset of disuse atrophy. – at Arkansas, USA
New work from @STsitkanou
and the lab. Transcriptomic profiles in the onset of disuse atrophy in both biological sexes.
@Franmorena98
@AReginaCabrera @eleanor_schrems @KevinMurachPhD @MuscleSciMegan
@UofA_ESRC
journals.physiology.org/doi/…
Stavroula Tsitkanou retweeted
PhD Opportunity #Myotwitter
If you are interested in the mechanisms regulating skeletal muscle adaptability then please apply to join my new lab @UCNZ, Christchurch, New Zealand!
tinyurl.com/SMUcP
Scholarships are available for stipend + tuition fees.
Please RT
Stavroula Tsitkanou retweeted
This was a big project. @WillDeaver led the study. @AReginaCabrera brought it home and many individuals put in countless hours. Really excited to get this data out there. Looking forward to continuing our work on biological sex dimorphisms in cachexia!
journals.physiology.org/doi/…
Stavroula Tsitkanou retweeted
Prof Aaron Russell and his IPAN team are working on improving the outlook for people with MND. Check out this great video from @FightMND and find out how this research is making a difference▶️
#fightMND #MND @Deakin @DeakinResearch @DeakinHealth
Professor Aaron Russell from @DeakinIPAN was recently awarded a FightMND IMPACT Grant.
Aaron’s project is exploring how MND is progressing and whether treatments are having their desired effect.
Learn more about Aaron's Grant at: youtu.be/a_SaEcDeACY
#FightMND #MND
The last two days have been so exciting in #APSSummit2023, presenting data from my study (@UACachexia) focused on the effectiveness of the SkQ1 mito- antioxidant on preventing cancer cachexia and receiving the Research Recognition Award in Cell & Molecular Physiology Section. – at Long Beach, CA
Stavroula Tsitkanou retweeted
Congratulations to IPAN Professor Aaron Russell on his @FightMND Impact Grant for his project aiming to understand the role of skeletal muscle in MND on-set and progression.
Stavroula Tsitkanou retweeted
In press!
@DelfinisLuca in our lab found cancer causes weakness in quads + diaphragm BEFORE atrophy
BUT quads recover 'specific' force once atrophy occurs
Can we embrace muscle heterogeneity and the power of compensation in mice to guide new therapies?
insight.jci.org/articles/vie…
Just excited about receiving the Young Investigator Award for my oral presentation at #SCWD22
Thanks @UACachexia and all lab colleagues and collaborators work hard on this project.
📌 Young Investigator Award: Congratulations @STsitkanou (USA) for the poster 4-22 “OPA1 over expression may protect against #cancer-induced #muscle wasting”
#SCWD22 #sarcopenia
Stavroula Tsitkanou retweeted
Our own @STsitkanou taking home the Young Investigator Award at #SCWD22!! Congrats Roula!!! And congrats to all of the trainees who presented their work this week! (Especially also @rejacabrera!!!)
📌 Young Investigator Award: Congratulations @STsitkanou (USA) for the poster 4-22 “OPA1 over expression may protect against #cancer-induced #muscle wasting”
#SCWD22 #sarcopenia