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Our lab focuses on brain imaging studies aiming to understand the large-scale brain networks implicated in human cognition and neurodegenerative disorders.

Yale School of Medicine
Joined August 2019
Photo by Jorge Sepulcre Lab (@SepulcreLab)Photo by Jorge Sepulcre Lab (@SepulcreLab)Photo by Jorge Sepulcre Lab (@SepulcreLab)Photo by Jorge Sepulcre Lab (@SepulcreLab)
Jorge Sepulcre Lab retweeted
Excited to see our work highlighted in today's New York Times article exploring the potential benefits of intentional mind wandering in creative thinking! nytimes.com/interactive/2025…
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Jorge Sepulcre Lab retweeted
Our latest work "Cortical Hubs of Highly Superior Autobiographical Memory" is now published in Cortex! We apply graph theory analysis in resting-state data to describe connectivity profiles associated with this rare form of enhanced memory. Full article: sciencedirect.com/science/ar…
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Jorge Sepulcre Lab retweeted
🧵Happy to share our last work on tau propagation and smell perception in aging. @LauraOrtizTeran @ThomasNgImaging @AlbersLab Marshall G @will_orwig Kim C @neuroeli Montal V @jokriolo @_PatriziaV Fahkri, Sperling R, Johnson K, @HeidiJacobsLab @SepulcreLab nature.com/articles/s41467-0…
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In a recent @NatureAging publication, researchers from @MGHMartinos and colleagues investigated early targeting of the locus coeruleus and how it may delay Alzheimer's progression. Read more: massgeneral.org/news/researc… @heidijacobslab @sepulcrelab @neuroeli @elouisekoops
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Jorge Sepulcre Lab retweeted
Join us in congratulating four of our 2023 #DistinguishedInvestigators 👏. These #DI will be honored at #RSNA23 in Chicago. For more program details, visit bit.ly/3M558k7.
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Jorge Sepulcre Lab retweeted
.@SepulcreLab and colleagues found that an #MRI shows how #ParkinsonsDisease (PD) disrupts neuronal circuits. Learn how these results lay the foundation for studying functional network reorganization at different stages of PD: spklr.io/6010iaGi
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Jorge Sepulcre Lab retweeted
In our latest research at @ICS_unav, together with @SepulcreLab, we show how belief networks are organized in different sociodemographic (ie male/female) and ideological (left-winger vs right-winger) groups. Check it out at @SpringerNature: rdcu.be/cUULm
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📢🥳Congratulations to @vmbotwin and colleagues for the publication "Network Tau spreading is vulnerable to the expression gradients of APOE and glutamatergic-related genes" in @ScienceTM @SepulcreLab @IIBSantPau 👇 science.org/doi/full/10.1126…
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Just published in @ScienceTM -- Network Tau spreading is vulnerable to the expression gradients of APOE and glutamatergic-related genes science.org/doi/full/10.1126…
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Jorge Sepulcre Lab retweeted
👏 Masterclass del Dr. Jorge Sepulcre, neurólogo y profesor de la Universidad de Harvard, sobre las redes cerebrales a gran escala implicadas en la cognición humana y los trastornos neurodegenerativos del Alzheimer. 📅 23/05 - 16h Inscríbete en ➡️ eventos.uloyola.es/83718/det…
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Interviews are ongoing for our #BehavioralNeurology-#Neuropsychiatry fellowship across the MGH Departments of Neurology @MGHNeurology & Psychiatry @MGHPsychiatry. 1 year & 2 year tracks available. Details below. @DickersonLabMGH @jacamprodon @SchmahmannLab @LRamirezGomezMD
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Jorge Sepulcre Lab retweeted
Network Neuroscience (2022) 6 (2): 320–338. Multimodal connectome biomarkers of cognitive and affective dysfunction in the common epilepsies. direct.mit.edu/netn/article/…
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Special Edition of CrossTalk next Tuesday (6/14) at 5pm EST. We welcome Kenji López-Alt (@kenjilopezalt) world-renowned chef to discuss the creativity and science of the culinary arts with Indre Viskontas (@indrevis). Click the link to register! crowdcast.io/e/tn68z5ea
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Jorge Sepulcre Lab retweeted
“Si no entendemos primero el cerebro, no vamos a entender cómo o por qué enferma”. El Dr. Jorge Sepulcre, neurólogo y profesor de medicina en @Harvard ha estado con nuestros estudiantes del área de #psicología para charlar sobre la conectómica. + info 👉 uloyola.es/blog/masteres/si-…
Also highlighted here: news.harvard.edu/gazette/sto… @MGHBrainHealth @MGHNeurology @MGHPsychiatry @MGHmapp co-senior author Jorge Sepulcre @SepulcreLab
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