Industry leader providing turn-key GPU workstations/clusters, computational tools, and tailored data processing service for the cryo-EM community and beyond.
San Diego/Boston/Amsterdam
Joined September 2016
- Tweets604
- Following2.1K
- Followers2.8K
- Likes2.1K
Local AI Powerhouse
Beyond #CryoEM: The SP AI Box is a universal local GPU workstation for ALL researchers. 🧬💻🛠
🚀 Now featuring OpenClaw deployment! Run an autonomous, private AI assistant directly on your local hardware.
✅ No token limit
✅ Full data privacy
✅ Local GPU-accelerated agents
Stop sending your data to the cloud. Own your AI.
🔗 singleparticle.com/aibox
#OpenSource #AI #OpenClaw #EdgeComputing #ResearchTech
🚨SURPLUS SALE: Workstation Upgrade🚨
We just upgraded our servers and have some high-performance components for sale. If you need to upgrade your #cryoEM workstation, DM us or contact sales via our website! (Priority to current SP customers).
Available hardware: 💾 Samsung 3.84TB SSDs ⚡️ 32GB DDR4 memory modules 🖥️ #Nvidia 3080 Turbo 10GB GPUs ⚙️ 8-GPU servers
Forwarded (still available. contact via email in the text):
nature.com/naturecareers/job…
Single Particle retweeted
Learn how our hunt for the native structure of top #antimalarial target PfATP4🧂led to the discovery of PfABP, an unknown essential binding partner, out now! @natcomms 👉 rdcu.be/eLRlH 🦠🔬❄️
A team effort by @mehsehret @cmholab & Anurag Shukla @AkhilVaidya1 #cryoEM
Single Particle retweeted
We’re looking for an enthusiastic postdoc to join our team. 😊
The project focuses on protein design and cryo-EM applied to cancer research. 🔬🧪
Position funded for 3 years.
Please share 🙏
Job description and details (deadline: October 11th): cnio.es/en/empleo/postdoctor…
Single Particle retweeted
We want you! Join the Department of Molecular and Cellular Biology @MoCel_Geneva at the University of Geneva @unige_en @UNIGEnews @sciences_UNIGE
and become our new colleague!
Assistant (tenure-track) Professor or Associate Professor! Please RT - thanks
jobs.unige.ch/www/wd_portal.…
🥪 Our partner DRTEM teams up with BESTRON for a mini lunchtime lecture at MC 2025 tomorrow!
🎁 FREE lunch — join us on Sep 1, 12:45–13:45, Room 8/9
Discover the latest:
🔬 In situ 4D-STEM detectors
📷 AI-ready CMOS cameras
🛠️ In situ holders
SingleParticle provides the GPU Workstation for Ptychography Reconstruction.
#MC2025 #4DSTEM #ElectronMicroscopy #Ptychography
Single Particle retweeted
We’re scaling structure as a core capability in AI-native drug design.
#TeamGenerate is searching for an Executive Director of CryoEM to lead a multidisciplinary team operating within one of the most advanced high-throughput structural biology platforms in the world. Reporting to our Chief Technology Officer, you’ll set the vision and deliver on the execution—expanding what’s possible in structural throughput and data quality. You’ll partner closely with machine learning, automation, and protein science teams to embed #cryoEM into a true design–build–test–learn loop.
This is an opportunity to shape a capability that will transform structural biology from a bottleneck into a high-speed engine for discovery—redefining how medicines are conceived, designed, and developed.
If this sounds like your next challenge, let’s talk.
generatebiomedicines.com/ope…
Single Particle retweeted
Join us at MPI-NAT in Göttingen for an exciting quest of #cryoEM dissection of #membranetrafficking. Please repost.
jobrxiv.org/job/max-planck-i…
Single Particle retweeted
ChimeraX daily builds can predict binding affinity of small molecules using Boltz 2 on your Mac, Windows or Linux computer. rbvi.ucsf.edu/chimerax/data/…
Single Particle retweeted
CryoDRGN-AI ❄️🐉🤖 is now published in @naturemethods!!! So excited to see this out and a huge congrats to @axlevy0 and team!
CryoDRGN-AI extends cryoDRGN from requiring input, fixed camera poses, to end-to-end ab initio reconstruction of biomolecules and their conformational landscapes!
Since our preprint, we have added ab initio reconstruction of cryo-ET subtomograms (@rishwanth_raghu @FeathersRyan 🙌) and several additional examples reconstructing large, messy datasets and discovery of new structures!
You can find a recent SBGrid webinar I gave about cryoDRGN-ET and cryoDRGN-AI here: youtube.com/watch?v=P9c1dUO3…
Paper: nature.com/articles/s41592-0…
A few more thoughts ⬇️ (1/3)
We present DRGN-AI for fast, ab initio cryo-EM reconstruction!
* learns a neural field from unposed images,
* designed for single-shot reconstruction of unfiltered datasets,
* finds new states missed by prior approaches!
Teamwork led by @ZhongingAlong
drgnai.cs.princeton.edu/ 1/
Single Particle retweeted
...And we're off! All packed and ready for #mmc2025 in Manchester next week 😀🔬🚛
We'll see you there - and if you haven't booked your ticket yet, there's still time! (Exhibition tickets are *FREE*) 👇
mmc-series.org.uk/general-in…
ALT RMS staff stand next to a van packed with items to take to mmc2025
🚀 New from Single Particle:
WhisperPro | 2025 – Now with 4D-STEM support
Graphene Grids – Alongside our trusted NiTi grids
VitroDrop – Portable cryo-plunger
🔗 Learn more: [singleparticle.com]
#CryoEM #CryoET #4DSTEM #GrapheneGrids #CryoPlunger
🚀 Single Particle is heading to #MMC2025 with exciting new products and services!
📍 Booth #504 – Come chat with our experts!
🖥️ Computation: WhisperPro GPU Workstation (now with 4D-STEM support)
🧪 Sample Prep: Graphene Grids, VitroDrop (portable cryo-plunger)
📷 Imaging: DRTEM Huangshan Timepix & Baiyun TEM CMOS Cameras
🔗 [singleparticle.com]
#MMC2025, #CryoEM, #ElectronMicroscopy, #4DSTEM
Single Particle retweeted
Ready to use #cryoEM for structural studies but need more training to get started? Want to use your home institution's resources to make data collection ready samples?
@NCCATinfo may be in your neck of the woods to help. Find us at @DBI_Science this May.
nccat.nysbc.org/del-sample-p…
🚀 A limited batch of RTX 4090 GPUs is now available.
Looking for a high-performance, cost-effective workstation?
📩 Reach out to customize your ideal setup:
👉 singleparticle.com/cryo-em-w…
#GPUWorkstation #RTX4090 #StructuralBiology
