Industry leader providing turn-key GPU workstations/clusters, computational tools, and tailored data processing service for the cryo-EM community and beyond.
San Diego/Boston/Amsterdam
Joined September 2016
- Tweets604
- Following2.1K
- Followers2.8K
- Likes2.1K
Single Particle retweeted
Learn how our hunt for the native structure of top #antimalarial target PfATP4🧂led to the discovery of PfABP, an unknown essential binding partner, out now! @natcomms 👉 rdcu.be/eLRlH 🦠🔬❄️
A team effort by @mehsehret @cmholab & Anurag Shukla @AkhilVaidya1 #cryoEM
Single Particle retweeted
We’re looking for an enthusiastic postdoc to join our team. 😊
The project focuses on protein design and cryo-EM applied to cancer research. 🔬🧪
Position funded for 3 years.
Please share 🙏
Job description and details (deadline: October 11th): cnio.es/en/empleo/postdoctor…
Single Particle retweeted
We want you! Join the Department of Molecular and Cellular Biology @MoCel_Geneva at the University of Geneva @unige_en @UNIGEnews @sciences_UNIGE
and become our new colleague!
Assistant (tenure-track) Professor or Associate Professor! Please RT - thanks
jobs.unige.ch/www/wd_portal.…
Single Particle retweeted
We’re scaling structure as a core capability in AI-native drug design.
#TeamGenerate is searching for an Executive Director of CryoEM to lead a multidisciplinary team operating within one of the most advanced high-throughput structural biology platforms in the world. Reporting to our Chief Technology Officer, you’ll set the vision and deliver on the execution—expanding what’s possible in structural throughput and data quality. You’ll partner closely with machine learning, automation, and protein science teams to embed #cryoEM into a true design–build–test–learn loop.
This is an opportunity to shape a capability that will transform structural biology from a bottleneck into a high-speed engine for discovery—redefining how medicines are conceived, designed, and developed.
If this sounds like your next challenge, let’s talk.
generatebiomedicines.com/ope…
Single Particle retweeted
Join us at MPI-NAT in Göttingen for an exciting quest of #cryoEM dissection of #membranetrafficking. Please repost.
jobrxiv.org/job/max-planck-i…
Single Particle retweeted
ChimeraX daily builds can predict binding affinity of small molecules using Boltz 2 on your Mac, Windows or Linux computer. rbvi.ucsf.edu/chimerax/data/…
Single Particle retweeted
CryoDRGN-AI ❄️🐉🤖 is now published in @naturemethods!!! So excited to see this out and a huge congrats to @axlevy0 and team!
CryoDRGN-AI extends cryoDRGN from requiring input, fixed camera poses, to end-to-end ab initio reconstruction of biomolecules and their conformational landscapes!
Since our preprint, we have added ab initio reconstruction of cryo-ET subtomograms (@rishwanth_raghu @FeathersRyan 🙌) and several additional examples reconstructing large, messy datasets and discovery of new structures!
You can find a recent SBGrid webinar I gave about cryoDRGN-ET and cryoDRGN-AI here: youtube.com/watch?v=P9c1dUO3…
Paper: nature.com/articles/s41592-0…
A few more thoughts ⬇️ (1/3)
We present DRGN-AI for fast, ab initio cryo-EM reconstruction!
* learns a neural field from unposed images,
* designed for single-shot reconstruction of unfiltered datasets,
* finds new states missed by prior approaches!
Teamwork led by @ZhongingAlong
drgnai.cs.princeton.edu/ 1/
Single Particle retweeted
...And we're off! All packed and ready for #mmc2025 in Manchester next week 😀🔬🚛
We'll see you there - and if you haven't booked your ticket yet, there's still time! (Exhibition tickets are *FREE*) 👇
mmc-series.org.uk/general-in…
ALT RMS staff stand next to a van packed with items to take to mmc2025
Single Particle retweeted
Ready to use #cryoEM for structural studies but need more training to get started? Want to use your home institution's resources to make data collection ready samples?
@NCCATinfo may be in your neck of the woods to help. Find us at @DBI_Science this May.
nccat.nysbc.org/del-sample-p…
Single Particle retweeted
GPCR drug discovery: new agents, targets and indications | Nature Reviews Drug Discovery
nature.com/articles/s41573-0…
Single Particle retweeted
Interesting in learning to process cryo-ET data in the latest version of Warp? I'll be running a workshop on April 22nd in central London, UK
details+registration: forms.gle/u4Hk73jhenMvpNBR9
Hope to see you there!
Single Particle retweeted
Ready for @MicroscopySoc #MM2025?
The call for papers is open for Microscopy & Microanalysis in Salt Lake City July 27-31, 2025.
Consider submitting papers to B01 (3DEM FIG).
Want to learn more? Go to: mmconference.microscopy.org & join our FIG!
In case you missed it... #MM2025 will be in Salt Lake City, Utah! 🌄
#MM2025 #Microscopy #Microanalysis #Science #Microscope #Biology #Microbiology #Research #SaltLakeCity #Utah #Conference
Single Particle retweeted
I encourage you to apply to join us at @UCBerkeley !
Scientific Director, Cal-Cryo. We're looking for an outstanding microscopist to run our cryo-EM facility (two Krioses and an Arctica). Apply now to join our outstanding community of cutting edge cryo-EM/ET researchers! tinyurl.com/ykasna3p
Single Particle retweeted
We are excited to announce the first Salamanca Biophysics Summer Course organized by Carlos Bustamante (@BustamanteLab) and Eva Nogales (@NogalesLab ). See the flyer below and consider applying!
Single Particle retweeted
The next #CryoEM Current Practices Webinar speaker will be @Vecchiology @Jacobs_Med_UB @UBuffalo on "Cryo-EM and fiducial marks as fail-safes for structural studies of very small membrane proteins" 12/12/2024 at 12 PM ET / 9AM PT
Sign-up today:
us02web.zoom.us/webinar/regi… as
Single Particle retweeted
Do you want to work at the interface of structural biology and #AI? We are #hiring Come to Paris for a @CNRS postdoc at @institutpasteur funded by @ERC_Research and co-supervised by @malletvincent Please RT!! #deeplearning #compbio More info here: research.pasteur.fr/b/vVT
Single Particle retweeted
We are looking for a #PhD student to study #MolecularMachines driving #membranetrafficking by #cryoEM #cryoET #temtomo. Image processing fans are particluarly welcome.
Single Particle retweeted
We recently spent a day in the lab with 2024 @NobelPrize winner and HHMI Investigator David Baker, where he discussed his groundbreaking work, the importance of basic science, and his passion for mentorship #NobelPrize
Single Particle retweeted
Congrats Prof Peijun Zhang won the annual The Center for Retrovirus Research Distinguished Research Career Award vet.osu.edu/research/center-…
Single Particle retweeted
Dear cryo-EM women scientists,
We want to honor you and your contributions at BPS 2025.
This year, the Cryo-EM subgroup will honor a mid/senior-career woman scientist as the inaugural June Almeida awardee.
June Almeida is the virologist who first discovered the coronavirus in 1967 using negative stain electron microscopy. Her story, like many women we know, is remarkable. womenshistory.org/education-…
It is in the spirit of June Almeida’s innovative research that this award is named. The awardee, in addition to receiving an honorarium, will present their research at the BPS CryoEM Subgroup Symposium. The deadline for nominations for the Almeida Award is November 1st, and details of the award and the application process can be found at (biophysics.org/Awards-Fundin…). Nomination packets should be sent to [email protected].
Questions? Contact @OliBClarke, me, @MeghnaG27 @PilarCossio2 or @10feng
♥️We sincerely hope to see you at BPS 2025 in LA to celebrate achievements and advances in cryo-EM!
