Soren Brage (@SorenBrage) profile picture

Soren Brage

@SorenBrage
 Cambridge, England
mrc-epid.cam.ac.uk/research/research-areas/physical-activity/
Joined August 2014
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  • Followers223
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Photo by Soren Brage (@SorenBrage)Photo by Soren Brage (@SorenBrage)Photo by Soren Brage (@SorenBrage)Photo by Soren Brage (@SorenBrage)Photo by Soren Brage (@SorenBrage)Photo by Soren Brage (@SorenBrage)
UK reference values of energy expenditure are out! biorxiv.org/content/10.1101/…
Descriptive epidemiology of energy expenditure in the UK: Findings from the National Diet and...

Descriptive epidemiology of energy expenditure in the UK: Findings from the National Diet and...

Background Little is known about population levels of energy expenditure as national surveillance systems typically employ only crude measures. The National Diet and Nutrition Survey (NDNS) in the UK...

biorxiv.org
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Causal link between physical fitness and cancer: nature.com/articles/s41416-0… Excellent work by Ellie Watts and @TomasIGonzales in @MRC_Epid collaboration with @theNCI
Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank...

Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank...

British Journal of Cancer - Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study

nature.com
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There is rightly much talk about using consumer wearable devices for physical activity measurement using various research study designs. We've written a commentary picking up on four key issues we think are relevant for population surveillance doi.org/10.1123/jmpb.2021-00…
Image from Tessa Strain (@tessastraining)
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Does it matter how you spend your calories on physical activity in terms of body composition? #FenlandStudy nature.com/articles/s41366-0…
Joint associations between objectively measured physical activity volume and intensity with body...

Joint associations between objectively measured physical activity volume and intensity with body...

International Journal of Obesity - Joint associations between objectively measured physical activity volume and intensity with body fatness: the Fenland study

nature.com
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Burn, baby, burn (those calories!) Metabolism peaks at age one and tanks after 60, study finds bbc.co.uk/news/health-581867…
Metabolism peaks at age one and tanks after 60, study finds

Metabolism peaks at age one and tanks after 60, study finds

Middle-aged spread cannot be blamed on a waning metabolism, according to researchers.

bbc.co.uk
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Compare recently published energy expenditure age trends with ditto from national UK estimates: academic.oup.com/ije/article…
Descriptive epidemiology of energy expenditure in the UK: findings from the National Diet and...

Descriptive epidemiology of energy expenditure in the UK: findings from the National Diet and...

AbstractBackground. Little is known about population levels of energy expenditure, as national surveillance systems typically employ only crude measures. T

academic.oup.com
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Check out Daily energy expenditure through the human life course science.sciencemag.org/conte…
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New paper out led by @pearce_matthew: "Is occupational physical activity associated with mortality in UK Biobank?" ijbnpa.biomedcentral.com/art…

Is occupational physical activity associated with mortality in UK Biobank?

International Journal of Behavioral Nutrition and Physical Activity - Current physical activity guidelines do not distinguish between activity accumulated in different behavioural domains but some...

link.springer.com
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Soren Brage retweeted
Eric Topol (@EricTopol) profile picture
Eric Topol
@EricTopol23 Jul 2021
Still find this counterintuitive? Study this diagram by @jburnmurdoch and @mroliverbarnes @FT ft.com/content/0f11b219-0f1b…
Image from Eric Topol (@EricTopol)
Eric Topol (@EricTopol) profile pictureEric Topol
@EricTopol23 Jul 2021
It's counterintuitive but simple math for why many people post-vaccination could be hospitalized for covid and vaccines are still 95% effective in preventing hospitalizations. Explainer: ft.com/content/a8c0f5f2-d27c… by @TimHarford @FT
Image from Eric Topol (@EricTopol)
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Future research by @ZhaoDylan @jrbperry & colleagues will examine how loss of function variants in GIGYF1 lead to increases in type 2 diabetes risk, and other links between biomarkers of biological ageing in adults and metabolic disorders. @NatureComms nature.com/articles/s41467-0…

GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health

Nature Communications - Mosaic loss of chromosome Y (LOY) is a common form of clonal mosaicism in leukocytes. Here, the authors extend genetic association analyses to rare variation using...

nature.com
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Unit scientist @jrbperry comments in @DailyMailUK on the identification of rare gene variants that dramatically increase type 2 #diabetes risk. This work involved reading complete DNA sequences of over 20,000 genes in >200,000 @uk_biobank participants. dailymail.co.uk/sciencetech/…
Gene increase your risk of Type 2 diabetes by six-fold, study finds

Gene increase your risk of Type 2 diabetes by six-fold, study finds 

Variants in a gene called GIGYF1 can increase the risk of developing Type 2 diabetes six-fold, report researchers at the University of Cambridge.

dailymail.com
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Volume or intensity. Why not both? @MRC_Epid @SorenBrage #MVPA #PAEE
medRxiv (@medrxivpreprint) profile picturemedRxiv@medrxivpreprint28 Mar 2021
Joint associations between objectively measured physical activity volume and intensity with body-fatness. The Fenland Study. medrxiv.org/cgi/content/shor… #medRxiv
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Challenges of global PA surveillance bmjopensem.bmj.com/cgi/conte… #WHO #GAPPA
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Replying to @imsepidemiology
@MRC_Epid is recruiting a Senior Data Manager to provide leadership in the processing and management of the diverse data we work with. Please share! More details (close 27/9): jobs.cam.ac.uk/job/26767/
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Largest ever study using wearable devices finds physical activity is beneficial for health, and more intense activity is better mrc-epid.cam.ac.uk/blog/larg… New #evidence from @tessastraining @PC_Dempsey @SorenBrage and colleagues.
Image from IMS Epidemiology, University of Cambridge (@imsepidemiology)
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Flurry of tweets there as very pleased our latest paper was published today. Thanks to @SorenBrage @PC_Dempsey and @MRC_Epid for doing all publication day duties. And to Jason Gill for nice commentary. Better go back to being on leave though 👋
Image from Tessa Strain (@tessastraining)
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Volume and intensity of activity both matter for mortality nature.com/articles/s41591-0…
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Soren Brage retweeted
medRxiv (@medrxivpreprint) profile picture
medRxiv@medrxivpreprint2 Jul 2020
Resting heart rate as a biomarker for tracking change in cardiorespiratory fitness of UK adults: The Fenland Study medrxiv.org/cgi/content/shor… #medRxiv
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Resting heart rate robust biomarker of fitness medrxiv.org/content/10.1101/…
Resting heart rate as a biomarker for tracking change in cardiorespiratory fitness of UK adults:...

Resting heart rate as a biomarker for tracking change in cardiorespiratory fitness of UK adults:...

Aims Resting heart rate (RHR) is inversely associated with cardiorespiratory fitness (CRF) but few studies have investigated the nature of this relationship in large population samples. We examined...

medrxiv.org
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This might help with creating positive public health messages Can complement existing 'burden of inactivity' messages with 'benefits of activity' messages (positive messaging recommended by @Chlobobs_ recent review ijbnpa.biomedcentral.com/art…)
Image from Paul Kelly (@narrowboat_paul)
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A story of accomplishment: doi.org/10.1016/S2214-109X(2…
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