Assistant Professor at DGIST @ Stem cell / Epigenetic biologist, Studing Human Development and Disease using Pluripotent Stem Cell
Korea
Joined April 2020
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Very excited to share our study is finally out in @CellCellPress. TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons: Cell cell.com/cell/fulltext/S0092…
Taewan Kim retweeted
After 16 wonderful years @WCMSurgery , I’m deeply honored to share that I will join @UCLAHealth @dgsomucla as Chair of Molecular & Medical Pharmacology in March 2027. Excited for this new chapter of science, innovation, and collaboration!
Very excited to share our study is out at JCI! Many thanks to a super amazing team of collaborators who make this possible!
Providing a new protocol for applications in cell therapy for #ParkinsonsDisease: doi.org/10.1172/JCI190954
Tae Wan Kim @TaeWanKim0 et al. @MSKCancerCenter introduce a refined method for producing dopamine neurons in vitro. The Boost+ differentiation protocol adds FGF18 and IWP2 treatment at the neurogenesis stage, improving yield, neuron subtype identity, and locomotor function in implanted rats.
The figure shows expression of midbrain dopamine neuronal markers FOXA2, TH, and EN1 in day 60 neurons.
Taewan Kim retweeted
Excited to share our new study uncovering and overcoming the molecular drivers of interspecies PSC competition to improve human chimerism in animals. Big congratulations to first authors Yingying, Hai-xian, and Saku, and to our collaborators! cell.com/cell/fulltext/S0092…
Specification of human brain regions with orthogonal gradients of WNT and SHH in organoids reveals patterning variations across cell lines: Cell Stem Cell cell.com/cell-stem-cell/full…
Taewan Kim retweeted
18 month data from the phase 1b single-arm, open-label clinical trial of AAV-GDNF in #Parkinsons by @ask_bio has been published; N=11; Well tolerated & associated with numerical stability (mild cohort; <5 yrs since dx) & improvement (moderate cohort)
movementdisorders.onlinelibr…
Taewan Kim retweeted
New data reveals region- & disease-specific changes in the levels of lipid species; Alterations in the levels of specific phosphatidylserine species in brain areas most affected in #Parkinsons; a-synuclein at mitochondria–ER membranes alters lipid metab.
nature.com/articles/s41531-0…
Specification of human brain regions with orthogonal gradients of WNT and SHH in organoids reveals patterning variations across cell lines: Cell Stem Cell cell.com/cell-stem-cell/full…
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Taewan Kim retweeted
Thrilled to share our review just published in @NeuroCellPress!
Big shoutout to Ava, Mengmeng , and our entire team!
authors.elsevier.com/a/1k-uh…
Taewan Kim retweeted
Early results from an MSK study shows a treatment for #Parkinson’s disease that involves creating nerve cells from embryonic stem cells and transplanting them into patients is safe and may improve Parkinson’s symptoms.
Read more via @NPR: n.pr/43ZW1v6
Taewan Kim retweeted
Dr. @TabarViviane and Dr. @studerl, physician-scientists at MSK, have developed a treatment for #Parkinson’s disease that involves creating nerve cells from embryonic stem cells and transplanting them into patients. Early results show the treatment is safe and may improve Parkinson’s symptoms.
"This is an important milestone on the road towards regenerative brain repair," says Dr. Tabar. "It represents more than two decades of collaborative work, based on very rigorous science beginning in our labs."
Learn more: bit.ly/3EvfKbB bit.ly/4lxH2yC
Taewan Kim retweeted
As stem cell-based modeling of the human nervous system and disease advances, we recently shared a group-effort framework in @Nature on designing experiments with #organoids, #assembloids, and transplantation
Here a few key takeaways in 6 slides👇
Great opportunity. If you are interested, please apply!
(Updated) DGIST 2025년 글로벌 포닥 지원사업 신규 공고(DGIST Global Postdoctoral Fellowship 2025 Announcement) | 채용정보 > BioJob | BRIC ibric.org/bric/biojob/recrui…
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Taewan Kim retweeted
New research from @ZivGanOr & colleagues finds that plasma glucosylceramide levels are regulated by ATP10D & are not involved in #Parkinsons pathogenesis; Results "suggest that altering GlcCer levels is not a good therapeutic method for GBA1-PD"
onlinelibrary.wiley.com/doi/…
Taewan Kim retweeted
Interesting: New research reports that isoforms of mitochondrial regulator PGC-1α are driven from distinct brain cell-type specific promotors, repressed with aging, & integral in coordinating metabolism & growth signaling
nature.com/articles/s41467-0…
Taewan Kim retweeted
Nothing to see here MAGA, just science casually treating hearing loss investor.regeneron.com/news-…
Taewan Kim retweeted
Online Now! Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation dlvr.it/THdkPb #stemcells
Taewan Kim retweeted
Excited to share our “Robust and inducible genome editing via an all-in-one prime editor in human pluripotent stem cells," is now published @NatureComms
nature.com/articles/s41467-0…
Taewan Kim retweeted
If you have young family members and want to attend scientific conferences, ISSCR provides Child and Dependent Care Grants @ISSCR #Hongkong isscr2025.org/care-grants
Taewan Kim retweeted
Stem cell therapies that work: 10 Breakthrough Technologies 2025
After years of controversy, stem cells are on the cusp of cures for conditions like epilepsy and type 1 diabetes
technologyreview.com/2025/01…
