Brenda Eap, PhD

Some of the biggest challenges in human health require new ways of thinking. ARPA-H is looking for the scientists, engineers, physicians, and other technical experts with bold ideas for tackling problems that have remained out of reach through conventional approaches. Program Managers at ARPA-H have the opportunity to develop and lead ambitious programs, bring together multidisciplinary teams, and move transformative ideas toward real-world health outcomes. For those with the expertise and a vision for what could be possible, this is an opportunity to turn that vision into action.

For years, critics have labeled Capitol Hill a "gerontocracy." The AP News Congressional Retirements Tracker shows a massive wave of lawmakers heading for the exits this election cycle, while underscoring a broader trend: Congress has steadily aged over the last century. While dozens of members are not seeking reelection to their current seats, many aren't stepping away from public life entirely, opting instead to pursue governorships or Senate seats. As a new generation of leaders steps up, we’ll be watching to see how the demographic landscape of Congress evolves. Nonetheless, the timing and opportunity for aging biology and longevity biotechnology have never been more ripe. At A4LI, we continue to champion this vision by advocating for policies that accelerate next-generation disease-modifying therapies. By pairing longer lifespans with vibrant healthspans, we ensure everyone has the energy to pursue what they love and the opportunity to pivot careers at any stage of life. Source: apnews.com/projects/2026-con…

What role should public policy play in extending healthy human lifespan? Our Founder, @dullunlivin, recently joined the @LongevityTech UNLOCKED podcast to discuss why advancing longevity science requires more than scientific breakthroughs. It also requires policies that help bring those breakthroughs to the people who need them. The conversation explores the growing momentum behind longevity policy, the challenges that remain, and why now is the time to rethink how governments approach healthy aging. 🎥 You can watch the full interview here: youtube.com/watch?v=LCl0oQ5k…

🧠 Longevity Fact of the Week 12.4 years. That's the average gap between lifespan and healthspan in the United States. In other words, the average American spends more than 12 years living with disease or disability before the end of life. While we have made remarkable progress in helping people live longer, the next challenge is helping people stay healthier for longer. At A4LI, we have made it our mission to advance policies that accelerate the development of therapies targeting the biology of aging, with the goal of extending not just lifespan, but healthspan as well. 📖 Learn more about the research behind the healthspan gap here: pmc.ncbi.nlm.nih.gov/article…

Last week, we hosted our biggest and most impactful D.C. Summit yet. Across three days, we welcomed 250+ attendees, brought together 60+ leaders across the biotech and policymaking space, and facilitated 40+ meetings between longevity stakeholders and Members of Congress. That is why NOW is the time we capitalize on this momentum. Here’s how you can help: 1️⃣ Back Our Petitions Pledge your support for our White Papers on Action Network (actionnetwork.org/groups/the…) to help key decision makers understand the importance of longevity science. 2️⃣ Share with your Network Every signature helps. Help us raise awareness for these initiatives. Thank you to everyone who attended this year’s Summit, as well as all of you who have supported us over the years. None of this would be possible without you. Together, we can create a world in which everyone can live healthier, longer lives.

Our H-SPAN Summit DC is just around the corner. This year, we’re building on last year’s conversation about cross-agency alignment in funding and regulatory frameworks for longevity. We are thrilled to close Day 2 of the Summit with a landmark session: “Building the Framework: Policy Levers for Longevity Innovation.” For the first time, senior administration leaders and Members of Congress will join in a singular forum to discuss current federal initiatives and legislative levers that set out to make healthy longevity a national priority and achieve a true "longevity dividend." Featured speakers for this policy-focused second day include: •Dr. Mehmet Oz (Tentative), Administrator of the Centers for Medicare & Medicaid Services (CMS) •Lowell M. Zeta, Acting Chief of Staff and Deputy Commissioner for Strategic Initiatives, U.S. Food and Drug Administration (FDA) •Dr. Alicia Jackson, Director of the Advanced Research Projects Agency for Health (ARPA-H) •Congressman Kevin Mullin (CA-14), Representative of the Bay Area Longevity Biotech Ecosystem •Congressman Jim McGovern (MA-2), Ranking Member of the House Rules Committee and Champion for Nutrition and Healthy Aging Policy •Congressman Paul Tonko (NY-20), Co-chair of the Congressional Longevity Science Caucus

Russia has committed $26 billion to longevity science, while China is advancing large-scale stem cell anti-aging trials and expanding aggressive investment in regenerative medicine and longevity biotechnology. Scientific leadership in longevity is rapidly becoming a defining frontier of global competitiveness. The United States cannot afford to sit on the sidelines. Join our letter campaign: actionnetwork.org/letters/th…

HB 1735 has passed the New Hampshire Senate. The bill was amended during the legislative process, but its passage reflects growing recognition that patients and innovators deserve greater flexibility when pursuing promising longevity therapies. "The final bill is more limited than we originally hoped for, but it's encouraging to see states like New Hampshire continue engaging with these issues,” said Dylan V. Livingston, Founder and CEO of @theA4LI. “The reality is that patients are looking for more options, and policymakers across the country are increasingly willing to have that conversation." We are grateful to the many New Hampshire leaders who championed HB 1735, including Governor @KellyAyotte and @NHSpeaker Sherman Packard. We also extend our thanks to the stakeholders, advocates, and volunteers who dedicated their time and energy to supporting the legislation and advancing the conversation around patient access and medical innovation.

Thank you for highlighting the momentum we have been building since our inaugural event in 2024, @LongevityTech! Incredible to see how far the conversation has moved from speculative science to serious national policy in just three years. Read it here: longevity.technology/news/h-… @bioagelabs @RetroBio_ @KarlPfleger @soniaarrison @mkaeberlein @DrMikeRoizen @BuckInstitute @aubreydegrey

The passage of HB 1734 and HB 1735 is a no-brainer, and it is disappointing how much pushback it is receiving from the “pro-business,” “pro-freedom” and “pro-life” Republicans on the Senate Health and Human Services Committee. There are countless lives that can be helped — from early stage chronic disease to rare disease patients, all of whom have no other options. If you live in NH, call your Senators and demand these bills get passed. If you know someone in NH, do the same. @KellyAyotte — thank you for your support, your leadership, and your ability to see things clearly and with reason. @roche4nh — you are making lives worse and actively hurting your state. As a pharmacist, you of all people should understand what’s at stake for patients who have run out of options. You still have a chance to get this right. Do the right thing.

The Alliance for Longevity Initiatives (A4LI) would like to provide an update regarding New Hampshire’s ongoing efforts to expand patient access to investigational medical treatments and strengthen the state’s position as a hub for biomedical innovation. This week, legislative language from HB1734 and HB1735 was successfully attached to SB504 through the amendment process in the New Hampshire House of Representatives, keeping these reforms active as negotiations continue. HB1734 would authorize the establishment of experimental treatment centers capable of offering eligible investigational therapies under state oversight, while HB1735 would expand New Hampshire’s Right to Try framework to include patients suffering from chronic and debilitating conditions We would especially like to thank House Speaker Sherman Packard (@NHSpeaker) and Majority Leader Jason Osborne (@Osborne4NH) for their leadership and continued support. Together, these proposals continue New Hampshire’s emergence as one of the most forward-looking states in the country on medical innovation, patient autonomy, and access to next-generation therapies. As the process continues, we encourage everyone to respectfully reach out to Senate President Sharon Carson, Senator Rochefort, and Senator Birdsell and urge them to support SB504 as amended during committee of conference negotiations. We look forward to continuing to work with lawmakers, patients, advocates, and innovators as this effort progresses.

𝐖𝐞 𝐚𝐫𝐞 𝐥𝐢𝐯𝐢𝐧𝐠 𝐥𝐨𝐧𝐠𝐞𝐫, 𝐛𝐮𝐭 𝐰𝐞 𝐚𝐫𝐞𝐧'𝐭 𝐥𝐢𝐯𝐢𝐧𝐠 𝐡𝐞𝐚𝐥𝐭𝐡𝐢𝐞𝐫. Sixty percent of the global disease burden is now tied to chronic, age-related conditions. We are trading quick deaths for decades of disability, and it’s time for the NIH to fund the solution, not just manage the decline. As the NIH requests input for its Strategic Plan for FY 2027-2031, the Alliance for Longevity Initiatives is proposing a Disease-Burden Framework. Our proposal recommends that research funding be allocated by actual disease burden, measured by DALYs (Disability-Adjusted Life Years) from the Global Burden of Disease Study. This isn't a new concept—a framework like this already exists with the Onco-Aging Consortium within the NCI and NIA. Now, it’s time to expand this successful model across all major disease institutes—NHLBI, NIDDK, NEI, NINDS, and NIDCD. 𝐖𝐡𝐢𝐜𝐡 𝐢𝐧𝐬𝐭𝐢𝐭𝐮𝐭𝐞 𝐝𝐨 𝐲𝐨𝐮 𝐭𝐡𝐢𝐧𝐤 𝐰𝐨𝐮𝐥𝐝 𝐛𝐞𝐧𝐞𝐟𝐢𝐭 𝐦𝐨𝐬𝐭 𝐟𝐫𝐨𝐦 𝐚 𝐟𝐨𝐫𝐦𝐚𝐥 𝐩𝐚𝐫𝐭𝐧𝐞𝐫𝐬𝐡𝐢𝐩 𝐰𝐢𝐭𝐡 𝐭𝐡𝐞 𝐍𝐈𝐀? 𝐋𝐞𝐭'𝐬 𝐝𝐢𝐬𝐜𝐮𝐬𝐬 𝐢𝐧 𝐭𝐡𝐞 𝐜𝐨𝐦𝐦𝐞𝐧𝐭𝐬. 𝐑𝐞𝐚𝐝 𝐭𝐡𝐞 𝐟𝐮𝐥𝐥 𝐩𝐫𝐨𝐩𝐨𝐬𝐚𝐥 𝐚𝐧𝐝 𝐬𝐢𝐠𝐧 𝐨𝐧 𝐲𝐨𝐮𝐫 𝐬𝐮𝐩𝐩𝐨𝐫𝐭: 🔗actionnetwork.org/petitions/…

Talks from our H-SPAN Arizona event are now uploaded on our YouTube channel: tinyurl.com/rxzztdm9 @azcommerce @AZTechWeek @ZuberLawler @VensureHR @ASU @UAZBIO5 @UAZPharmacy @BuckInstitute @Hexoskin @GoldwaterInst @OraBiomedical