Medicinal Chemist at BMS | PhD with @TheNelsonLab | DePaul University Alum '18
Cambridge, MA
Joined June 2020
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Just in time for the holidays! Very excited to see our work on catalytic asymmetric vinyl cation C–H insertion reactions in @ScienceMagazine this week, and huge congrats to all who made this project possible! @sep_funnel @bwigmonster @Sigman_Lab @houk1000
Also this week, @sep_funnel @chemchlo and collaborators in @TheNelsonLab @Sigman_Lab and @houk1000 get asymmetric induction at vinyl cations with List-type imidodiphosphorimidate chiral counterions science.org/doi/10.1126/scie…
Chloe Williams retweeted
Congratulations to @GabrielLovinger and Marcus Sak @msh_yi on their paper in @Nature! A HBD catalyst accelerates an SN2 pathway despite H-bonding to the nucleophile by preorganizing the ion pair into a reactive conformation, just like an enzyme would!
nature.com/articles/s41586-0…
The final chapter of my PhD is officially out!
Main Group-Catalyzed Cationic Claisen Rearrangements via Vinyl Carbocations | Organic Letters pubs.acs.org/doi/10.1021/acs…
Chloe Williams retweeted
Plus out in First Release from @CornellaLab it’s 1-coordinate triplet bismuth! science.org/doi/10.1126/scie…
Great to see this project wrapped up!
pubs.acs.org/doi/10.1021/acs…
Chloe Williams retweeted
Our most recent chemoenzymatic synthesis story is out! Congratulations to @EvanORomero, @JCPerkins23 and collaborators from the @TheNelsonLab! Non hemes for the win! #BioCats Chemoenzymatic Synthesis of (+)-Xyloketal B pubs.acs.org/doi/10.1021/acs…
Last year's Corteva Chemistry Scholars Symposium was a blast--definitely be sure to apply!!
Calling all organic chemists!!! Applications are open for the 2023 Corteva Chemistry Scholars Symposium!!! This is not a drill!!!
I. am. PUMPED!!!!!!! Please share with your friends and enemies, because if you both come to this I bet you'll become besties...
#cortevascholars2023
Chloe Williams retweeted
Research Highlight now online:
Positive insertions
nature.com/articles/s44160-0… ($)
Highlighting the @ScienceMagazine Article by @sep_funnel, @chemchlo and co-workers in the @TheNelsonLab, @Sigman_Lab and @houk1000 groups
Chloe Williams retweeted
Looking for a new opportunity in 2023? Consider joining the @NarayanLab team as a lab manager/research staff person #biocatalysis #chemtwitter #chemjobs
Research Lab Specialist Assoc g.co/kgs/RXq6k9
Chloe Williams retweeted
In a paper published in the journal Science, Professor Hosea Nelson describes a new technique devised in his lab that allows for the precise selection of molecular handedness in chemical reactions.
cce.caltech.edu/news-and-eve…
Chloe Williams retweeted
Hosea Nelson (PhD '13; @TheNelsonLab), Caltech professor of chemistry, led the development of a new technique that allows for the precise selection of molecular handedness in chemical reactions.
caltech.edu/about/news/takin…
Chloe Williams retweeted
“The idea that carbocations as reactive as unstabilized vinyl cations could be engaged in highly enantioselective reactions would have seemed quite unlikely until recently,” says Harvard University’s Eric N. Jacobsen. fal.cn/3unb2
Chloe Williams retweeted
I'm really excited to see this story finally out in @ScienceMagazine! Big shout out to my project mates @chemchlo @bwigmonster Stasik and awesome collaborators @Sigman_Lab Brittany @werthwhilejake Jonathan @houk1000 for making this project an awesome journey
Also this week, @sep_funnel @chemchlo and collaborators in @TheNelsonLab @Sigman_Lab and @houk1000 get asymmetric induction at vinyl cations with List-type imidodiphosphorimidate chiral counterions science.org/doi/10.1126/scie…
Chloe Williams retweeted
Great piece by Beth @beth_halford as well. It’s refreshing to see a story driven by quotes from trainees …. We all know they did all the work! Taming the vinyl carbocation cen.acs.org/synthesis/Chemis… via @cenmag
Chloe Williams retweeted
Thanks @beth_halford for covering our work! Taming the vinyl carbocation cen.acs.org/synthesis/Chemis… via @cenmag
Chloe Williams retweeted
A terrific visit to Caltech for the BMS symposium with Rebecca Green @rebeccois from #BMSChemistry. It was great to catch up with old friends @FuLabCaltech, @sarah_reisman, @brianstoltsz70 and meet an amazing group of students.
Chloe Williams retweeted
At least 234 people, including 29 children have been killed in the Iranian nation's ongoing protests against the Islamic Republic, which started 40 days ago following the death in custody of Mahsa Amini, according to the Oslo-based @IranHRights.
Chloe Williams retweeted
A huge fire blazed at a notorious prison where political prisoners and anti-government activists are kept in the Iranian capital ti.me/3CBnx2D
Chloe Williams retweeted
Thank you @VP Harris for meeting with me to discussed how the U.S. will make sure the voices of Iranian protesters are heard, and that Iranian officials are held accountable for their brutality and abuses.
#MahsaAmini #IranProtests
whitehouse.gov/briefing-room…
I met Nazanin Boniadi today to discuss the peaceful protests in Iran. The women and girls who are risking their lives to stand up for equal rights and basic human dignity are an inspiration to all of us around the world. We see you and we stand with you.
ALT Vice President Harris sits with Nazanin Boniadi in her West Wing office.
