Pinned Tweet
Our work on transcription factor-wide CRISPR screen identifying essential TFs for stem cell pluripotency is officially out @CellReports!🎉 Special thanks to my advisor @EstebanMazzoni and collaborators @nevillesanjana and @congyilv for this great work!
cell.com/cell-reports/fullte…
Gorkem Garipler, PhD retweeted
We have something exciting to share from @Conception.
We generated human early egg cells (primary oocytes) from stem cells through in vitro gametogenesis, or IVG.
Gorkem Garipler, PhD retweeted
I’m so excited to share this update on @Conception –
We’ve generated the first early human eggs derived from stem cells.
This is a big deal -- the potential to redefine fertility is real.
We made human eggs from stem cells!
I'm incredibly proud to be part of the amazing team at @Conception that made this milestone possible.
Check out our latest blog post summarizing our findings and what they mean for the future of reproductive biology! conception.bio/science-and-u…
Gorkem Garipler, PhD retweeted
Conception’s mission is to turn stem cells into human eggs and redefine fertility.
We have an exciting update - we've generated the first early human egg cells derived from stem cells.
Super excited to share our latest publication
@NatureComms
identifying transcription factors required for neuronal differentiation with a CRISPR KO screen! 🥳 Coming from a great team w @congyilv @chaodai @nevillesanjana @EstebanMazzoni 🚀
TWEETORIAL time! In new work, we identify required transcription factors for neural differentiation using a TFome-wide CRISPR knock-out library.
Congrats to first authors @congyiliv and @chaodai (from our lab) and @ggaripler (from @estebanmazzoni lab). 👏👏👏
Gorkem Garipler, PhD retweeted
Asla unutturmayacağımız bir gün… 20 yıldır karşı devrimle mücadele eden Mustafa Kemal’in askeri İzmirlilere bugün, mutant gazetecilerin borazanlığında, Davutoğlu’nu, Babacan’ı, kumpasçı The Taraf yazarını alkışlatacaklar
Gorkem Garipler, PhD retweeted
AKP artıkları, eski partilerindeki tek adam zihniyetini aynen Millet İttifakı'na taşımış görünüyorlar. Bu tipler hiçbir zaman demokrasiyi içlerine sindiremediklerinden dolayı, sürekli her bulundukları ortamda "tek adam, tek seçenek" yaratma gayreti içinde oluyorlar. Milletimiz "tek adam" dayatmalarına seçim günü sandıkta gereken cevabı verecektir.
Gorkem Garipler, PhD retweeted
Sayın Ali Babacan'ın hakkımda söylediği "Bizim eskiden de bir hukukumuz yok ki Sayın İnce'yle" sözü, sonuna kadar doğru. Benim ne geçmişte ne de bugün bu tiplerle bir hukukum olmadı, olmayacak.
Gorkem Garipler, PhD retweeted
My final first author paper from PhD got published in @FrontNeurosci!
Big thanks to the team, esp. @EstebanMazzoni, @mahonylab, N.Flames for pushing it thru. It was a humbling experience to decode & program distinct neuronal subtypes with TF combinations
frontiersin.org/articles/10.…
Gorkem Garipler, PhD retweeted
Holy grail of human reprogramming published @Nature : Chemical reprogramming of human somatic cells to pluripotent stem cells nature.com/articles/s41586-0…
Gorkem Garipler, PhD retweeted
Analysis of haploinsufficiency in human embryonic stem cells with a unique system that allowed the generation of a genome-wide heterozygous mutant library. Kudos to Roni Sarel-Gallily! cell.com/cell-reports/fullte… @CellReports
Gorkem Garipler, PhD retweeted
We are looking to recruit a postdoctoral fellow to work on chromatin modifiers in reprogramming, induced pluripotent stem cells and blastoid models of early human development. 🔬🧫🧬
See : scl.ku.edu.tr/ for info about our lab.
And please share!
Gorkem Garipler, PhD retweeted
Our latest paper is online @CellStemCell! Capybara: A computational tool to measure cell identity and fate transitions cell.com/cell-stem-cell/full… led by @WenjunK
Super excited to share our latest publication @CellStemCell describing a new resource for measuring cell identity during differentiation and reprogramming! This great work is led by @WenjunK and @morris_lab. Congrats to all authors! @EstebanMazzoni
Our latest paper is online @CellStemCell! Capybara: A computational tool to measure cell identity and fate transitions cell.com/cell-stem-cell/full… led by @WenjunK
Gorkem Garipler, PhD retweeted
Drs. Görkem Garipler (@ggaripler) and Congyi Lu (@congyilv) used a #CRISPR screen to identify ZBTB11 and ZFP131 as required transcription factors for #pluripotency.
🖇️ Read the @CellReports paper from Dr. @EstebanMazzoni's group: bit.ly/3tadJsR
Gorkem Garipler, PhD retweeted
This is really great work from @ggaripler and @congyilv, using a CRISPR screen against all TFs to find two new zinc-finger regulators of pluripotency. Lexi Morrissey from our lab helped characterize the genomic binding of those TFs.
This is Finally out!
Beautiful work by @ggaripler with @nevillesanjana @mahonylab identifying a pair of TF that maintain pluripotency by repressing pro-differentiation genes
cell.com/cell-reports/fullte…
Gorkem Garipler, PhD retweeted
Congrats to @congyilv from our group and @ggaripler from @EstebanMazzoni lab on this new study that uses TFome-wide CRISPR libraries (🐭 & 🧑🤝🧑) to find essential TFs to maintain pluripotency. 👏
Stay posted for more great work from Congyi & Gorkem still to come.... 🙂
This is Finally out!
Beautiful work by @ggaripler with @nevillesanjana @mahonylab identifying a pair of TF that maintain pluripotency by repressing pro-differentiation genes
cell.com/cell-reports/fullte…
Gorkem Garipler, PhD retweeted
This is Finally out!
Beautiful work by @ggaripler with @nevillesanjana @mahonylab identifying a pair of TF that maintain pluripotency by repressing pro-differentiation genes
cell.com/cell-reports/fullte…
Many thanks to our amazing collaborators @mahonylab for their analysis during identifying mechanisms of these TFs, @uwe_ohler & @lsofialz for their input on screen analysis, and to the rest of the team @YingzhenP @Anazenfiore @begum_aydin_ @SimonVidalV!