Martin Humphries Lab, University of Manchester. Investigating the molecular basis of adhesion receptor signalling.
Manchester, UK
Joined January 2010
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nitter.cf/JCellBiol/status/12765…
And now it's the latest lab manuscript out in @JCellBiol
Well done @MeganChastney and colleagues
Just out in @biorxivpreprint: New insights on the integrin adhesome from @MeganChastney
Martin Humphries Lab retweeted
Our work on ‘sub-tumor microenvironments in #PancreaticCancer, out in Cell 😀🎉
Major kudos to the amazing team @pmcancercentre @OICR_news, @UniFreiburg and co-PIs @KislingerThomas, Melanie Börries, Steve Gallinger and @rmkhokha!
cell.com/cell/fulltext/S0092…
Martin Humphries Lab retweeted
Excited to share new optogenetic and analytical techniques to infer nuclear entry & exit rates of YAP1and bound fractions of proteins of interest @J_Cell_Sci doi.org/10.1016/j.cels.2018.… and doi.org/10.1007/s00285-021-0… Key points in linked tweets 👇 1/6
Martin Humphries Lab retweeted
NEW: as we get more and more studies on vaccine efficacy, it becomes harder to distill their results into one clean summary.
Here's my attempt at showing 22 results from 4 studies of 3 vaccines and 2 efficacy measures in 1 graphic, with @donatopmancini ft.com/content/5a24d39a-a702…
Martin Humphries Lab retweeted
We just updated our large database of 387 postdoctoral fellowships, listing description of the fellowship, $ amount, deadline, and eligibility.
Download the database here: research.jhu.edu/rdt/funding…
This looks interesting. Magliozzi, JO & Moseley, JB. Pak1 kinase controls cell shape through ribonucleoprotein granules. bioRxiv posted 29 June 2021 doi:10.1101/2021.02.17.431635. biorxiv.org/cgi/content/abst…
Martin Humphries Lab retweeted
Kindlin-3 disrupts an intersubunit association in the integrin LFA1 to trigger positive feedback activation by Rap1 and talin1 stke.sciencemag.org/content/…
Martin Humphries Lab retweeted
My first, first author paper is out in @jbiolchem 😊
@bengoult @MJ_Humphries @DrMCJones33 jbc.org/article/S0021-9258(2…
Martin Humphries Lab retweeted
Very happy that Megan's paper has just been published in Current Biology. Well done to Megan and the whole team! This paper nicely shows how tissue-wide mechanics and cell division can be affected by a small cluster of oncogenic cells.
sciencedirect.com/science/ar…
Martin Humphries Lab retweeted
The Ting lab is looking for postdocs interested in developing molecular technologies for recording, manipulating & discovering cellular behavior.
We use state-of-the-art protein engineering, directed evolution, chemical synthesis, microscopy & proteomics. Email Alice to apply!
Martin Humphries Lab retweeted
Manuscript accepted (more on this soon) and promoted to full professor! So grateful to our passionate @csunoncogene members; my mentors/collaborators; my administrators @csunorthridge/@CSUNBIO; and the support (ie, #ASCBMAC, @FulbrightPrgrm and @NIH) that have made this possible. – at Los Angeles, CA
Martin Humphries Lab retweeted
In the June issue of Cancer Discovery, Mechanisms of resistance to KRASG12C-targeted therapy. @DavidHongMD @AkhaveNeal @MDAndersonNews
bit.ly/3pFe2bI
Martin Humphries Lab retweeted
We are looking for a junior group leader to join us @WTcell. If you are looking to set up a research group in a highly collaborative environment in a great city, here is your chance! Open call for anything cell biology related.
Research Group Leader – Wellcome Centre for Cell Biology
Wellcome Centre for Cell Biology (@WTcell), School of Biological Sciences, University of Edinburgh, UK
jobrxiv.org/job/wellcome-cen…
#ScienceJobs #sciencecareers #universityjobs
Martin Humphries Lab retweeted
So today was my last day in @humphrieslab at @wtccmr @FBMH_UoM Thanks to all past and present lab members (too many to mention here) for making it such a great experience. Special thanks to @MJ_Humphries for employing me for so long (since 1997!).
Kalli M, et al. Mechanical stress in pancreatic cancer: Signaling pathway adaptation activates cytoskeletal remodeling and enhances cell migration. bioRxiv posted 11 June 2021 doi:10.1101/2021.06.11.448065. biorxiv.org/cgi/content/abst…
Steenkiste EM, et al. A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics. bioRxiv posted 9 June 2021 doi:10.1101/2021.01.29.428899. biorxiv.org/cgi/content/abst…
Martin Humphries Lab retweeted
Data about Alpha (Kent) & Delta (India) variants since Feb 2021 from @PHE_uk
Cases A 138,774 D 9427
A&E visit A 5.6% D 5.1%
Hospital stay A 1.5% D 0.9%
Death A 1.2% D 0.2%
Unadjusted data without testing bias etc accounted 4 BUT reducing % for D vs A from A&E 2 death is 👍🤞