@CRUK_MI Manchester Institute Fellow/Group Leader Hon Con. Haematologist @TheChristieNHS Former @aacr @CR_UK Transatlantic Fellow DFCI
United Kingdom
Joined December 2012
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Thanks to @LeukUK and all their supporters- looking forward to starting this project with the post-doc!
cruk.manchester.ac.uk/career…
📢 We’re funding two new groundbreaking research studies investigating the genetic changes that can lead to acute myeloid leukaemia (AML).
Meet our first John Goldman Fellow for 2026: Dr Justin Loke @jloke1 from @OfficialUoM.
Read more about his research: leukaemiauk.org.uk/research-…
findaphd.com/phds/project/mc…
Interested in a PhD?- are you a medical student? TP53-mutant acute erythroid leukaemia is among the most difficult cancers to treat and may rely on surrounding cells for survival.
We’d love to welcome a medical student to join us for a three-year project exploring which cells provide this support—and whether disrupting it kills the leukaemia.
You’ll combine CRISPR mouse models with imaging of patient bone marrow to help answer this important question.
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This MB-PhD studentship is based at Manchester Cancer Research Centre. Apply by Monday, 15 March 2027, and see the link above for eligibility details.
Interested or curious to learn more?-please message me or email:
[email protected]
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Justin Loke retweeted
📢 Fully funded clinical PhD studentship available in my group! @MCRCnews @CR_UK @OfficialUoM
❓Can we wake up an ageing immune system to fight leukaemia? Our preliminary data suggest yes! 😎
More details at the link 👉findaphd.com/phds/project/mc…
Justin Loke retweeted
📢 We’re funding two new groundbreaking research studies investigating the genetic changes that can lead to acute myeloid leukaemia (AML).
Meet our first John Goldman Fellow for 2026: Dr Justin Loke @jloke1 from @OfficialUoM.
Read more about his research: leukaemiauk.org.uk/research-…
I'm recruiting a postdoc, Myeloid Cancer Biology, at @CRUK_MI.
Funded by: John Goldman Fellowship from @LeukUK .
@ASH_hematology
Problem: people with germline predisposition to AML/MDS carry a high lifetime risk, but which combinations of mutations drive disease?
Existing models can't recreate the multi-mutation genotypes patients actually have.
Our approach: a transgenic Cas12a platform disrupting up to 4 loci simultaneously in single HSPCs.
Paired with in vivo transplantation, flow, histopathology and single-cell multiome
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You will play an important role in how the lab develops alongside key clinical and scientific teams, in the Paterson Building @CRUK_MI attached to @TheChristieNHS.
Come join!
£39,253–£47,543. 11 Oct 2026.
[email protected]
cruk.manchester.ac.uk/career…
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Engineer blood cancer to defeat it!👨🔬👩🔬
I'm hiring a Senior Scientific Officer at the CRUK Manchester Institute — using CRISPR to recreate the mutation combinations behind AML and MDS, and find where they're vulnerable. Hands-on. Apply 👇
apps.cruk.manchester.ac.uk/r…...
Happy to discuss if you are interested in a Summer placement in Manchester!
Thinking about an MB-PhD? Our summer placements give Manchester, Leeds and St Andrews MBChB students a unique insight into clinical academia.
Spend a week in labs, meet researchers, and explore our MB-PhD studentships. 🎓🚀
Applications are now open: ow.ly/T9BR50YXwHW
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Justin Loke retweeted
🚨 PhD applications now open!
We're offering CRUK-funded Clinical & Non-Clinical PhD opportunities starting in 2026 at the CRUK Manchester Centre. 🧬
📅 Apply by Monday 17 Nov 2025
🔬 Explore our projects: crukcentre.manchester.ac.uk/…
New opportunity - this is a non clinical PhD 4 year program - have a look and DM me if wish to discuss this particular student ship in decoding high risk Leukemia.
If that doesn’t take your fancy - there are plenty of exciting projects here! 🤓
cruk.manchester.ac.uk/phd-st…
Interested in PhD in CRISPR engineering to develop new models of myeloid malignancies?!
Join me @CRUK_MI
crukcentre.manchester.ac.uk/…
For Clinically trained applicants-DM if you have queries
Deadline 17th November 2025
Justin Loke retweeted
Congratulations @jloke1 Ben Ebert & colleagues on their outstanding work identifying a novel mechanism of Tet2-mutant clonal hematopoiesis. It was a pleasure to feature this at Best of ASH! #ASH24 @ASH_hematology
Very cool to have @TrowbridgeLab explaining our work so eloquently! Watched with the team whilst waiting our flight!
Thank you and to @ASH_hematology for selecting this abstract
Very cool to have @TrowbridgeLab explaining our work so eloquently! Watched with the team whilst waiting our flight!
Thank you and to @ASH_hematology for selecting this abstract