MD-PhD student @UWMedicine @uwepidemiology working on genomic epi of emerging infections with @trvrb | @Yale BS/MPH | 🏳️🌈 he/him/él | 🇨🇴 pa’lante, mi gente
Seattle, WA
Joined December 2013
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Extremely honored and ecstatic to be named a 2024 #STATWunderkind ! Many thanks to @statnews for highlighting my work on using genomic epi and phylodynamics to understand mpox dynamics affecting queer communities around the globe. Read more here: statnews.com/meet-the-2024-s…
Miguel Paredes retweeted
Today @CAPublicHealth confirmed the first known case of clade I mpox in the United States related to the outbreak in Central and Eastern Africa. CDC is awaiting the specimen for confirmation testing, assisting our state and local partners to understand more about this case and prevent mpox spread in the United States. Read full statement: cdc.gov/media/releases/s1116…
Miguel Paredes retweeted
ARTIC have primers for
#Marburg virus! (#MVD)
labs.primalscheme.com/detail…...
#molecularepidemiology #pathogen #pathogensurviellance #bioinformatics #epidemiology #virus #outbreak #clinicalvirology
Miguel Paredes retweeted
Deep mutational scanning of H5 #influenza by @bdadonai @jbloom_lab &co reveals how the >10,000 possible amino-acid mutations in #hemagglutinin affect cell entry, receptor preference, protein stability & neutralization by antibodies #H5N1 #PLOSBiology plos.io/3O3PaHI
Miguel Paredes retweeted
WHO: FIRST LOCAL TRANSMISSIONS OF MPOX CLADE IB IN THE WHO EUROPEAN REGION CONFIRMED IN THE UK
Miguel Paredes retweeted
I’m excited to see our paper posted @medrxivpreprint showing that older folks have higher levels of antibodies that recognize H5N1 viruses compared to younger individuals. Finally some good news for old people. 1/12 medrxiv.org/content/10.1101/…
Miguel Paredes retweeted
The Oropouche virus expansion in Brazil was a concerning case of arbovirus emergence outside of its endemic range, and so many questions remained!
We aimed to answer some of them by integrating landscape phylogeography and ecological niche modelling!
medrxiv.org/content/10.1101/…
Miguel Paredes retweeted
Wow. The human isolate of the Texas cattle H5N1 is way more transmissible by aerosols in ferrets than the bovine isolates tested so far.
Another warning that we shouldn’t assume that H5N1 in people is always going to be mild & limited to conjunctivitis.
nature.com/articles/s41586-0…
Miguel Paredes retweeted
Yale has renewed its Scholars At Risk program for 2025.
If you’re a PhD scientist facing violence or persecution in your home community, you can get a funded position to work at @Yale or @YaleMed for up to two years.
Nominations due Dec 1.
world.yale.edu/resources/sch…
Miguel Paredes retweeted
Trump has talked about immigrants having "bad genes" or "poisoning the blood of the country"
to experts we talked to, it sounded like 1920s eugenicists
we wrote abt the history — but also the ways academia has unintentionally upheld ideas abt biological differences btwn groups
Miguel Paredes retweeted
We are recruiting up to 5 Pandemic Sciences Research Fellows at @UniofOxford. Posts are for recent graduates to carry out independent research on topics in one or more of the following areas: AI & Epi, Genomics, Climate & Infectious diseases, Global health digital data science ↓
Miguel Paredes retweeted
rdcu.be/dYl8U
#oropouche @Antonio33716006
Given the complex interactions between climate change, env. modification, urban growth &human mobility, lack of effective surveillance will continue to facilitate the (re-)emergence of pathogens with potential epidemic capacity
Miguel Paredes retweeted
APOBEC3 deaminase editing supports human-to-human transmission in escalating Mpox outbreaks of both Clade Ia and Ib in Kinshasa, Democratic Republic of the Congo, July-September 2024.
virological.org/t/apobec3-de….
Miguel Paredes retweeted
Thinking about doing a postdoc? Wondering what we do all day?? @chris_zie @sofiavanmoorsel and I tracked over 19 months (!) of work & compared it to our junior postdoc data from 6 yrs ago - check out our article! #AcademicChatter #AcademicTwitter #phdchat elisagranato.com/days-in-the…
Miguel Paredes retweeted
Excited this paper is out in @Nature on the global genomic surveillance of #monkeypox virus.
Honored to have the opportunity to work on this and huge thanks to everyone for their efforts
Our analysis reveals
- high mobility of clade I viruses within Central Africa
- sustained human-to-human transmission of clade IIb lineage A viruses within the Eastern Mediterranean region
- distinct mutational signatures that can distinguish sustained human-to-human from animal-to-animal transmission.
- distinct clade I sequences from Sudan suggest local MPXV circulation in areas of Eastern Africa over the past four decades.
nature.com/articles/s41591-0…
An inspiring profile of a very kind and brilliant role model @NathanLo3579
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Miguel Paredes retweeted
Last chance to fill in our BEAST2 survey! Have your say while you can :) Thanks for all those of you that already have!
Want to have your say about BEAST2 future developments?
Fill in our BEAST2 user and developer survey :)
forms.gle/WjELzgvDUuxCKhSAA
A cool example of how evolution and public health go hand in hand!
Take a look at my essay for Nature Reviews Genetics! It's pretty cool but behind a paywall :-(
Let me know if you'd like a copy.
nature.com/articles/s41576-0…
Miguel Paredes retweeted
A few points on recent developments in the Marburg response:
- We’ve sequenced the virus genomes from three branches of a single cluster.
- Using genomic tools, we found that all sequences share a single zoonotic origin, meaning the virus jumped from animal to human just once.
Miguel Paredes retweeted
New epidemiologic report on mpox cases in Burundi following the introduction of Clade Ib virus reveals a median infection age of 9.5 years, with most cases concentrated in Bujumbura.
Kudos to Alexis Nizigiyimana & team, published today in @Eurosurveillanc.
tinyurl.com/5a4pyx3t
