CRI Fellow @WherryLab @Penn 🇺🇸 | previously @LMackayLab 🇦🇺 | @ForbesUnder30 '22 | T cells in infection, cancer and everywhere in between 👩🔬🌜
Philadelphia, PA
Joined March 2009
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Are all skin TRM cells created equal? Beyond excited to share our new paper in @ScienceMagazine, where we show diverse CD8+ TRM use distinct molecular pathways to develop and persist in skin, which we can target to fine-tune the skin-immune landscape🧵👇🏻 science.org/doi/10.1126/scie…
Simone Park retweeted
Excited to share my graduate work from the @EJohnWherry lab on the molecular mechanisms locking in the differentiation fate of exhausted CD8 T cells (Tex), published earlier this month in @SciImmuno. Main findings below!
science.org/doi/10.1126/scii…
Simone Park retweeted
Our latest study, led by @susanna_c_, shows CD47 × PD-L1 bispecific antibodies enhance tumor-resident CD8+ T cell responses, boosting anti-tumor immunity. Grateful to partner with @PfizerOncMed to advance cancer research! 🔬
@TheDohertyInst
onlinelibrary.wiley.com/doi/…
Simone Park retweeted
1/ 🚨 Hot off the press! 🚨Our new paper, led by @ObersAndreas & @maxevrard, is now live in @ImmunityCP! 🧬 Curious how CD8+ tissue-resident memory T cells (TRM) adopt their fate in different organs? Let’s dive in! 🧵👇
authors.elsevier.com/c/1jw~j…
Simone Park retweeted
Very happy to share this new work on LAG3 and PD1. Has been a long road to (begin to) sort out how LAG3 functions in CD8 T cell exhaustion. Great work by Shin Ngiow and super collaboration (and 2 other great papers) with @Vignali_Lab and Dario Vignali cell.com/cell/abstract/S0092…
and also excited today to see @divijmathew paper from the lab online now in @ScienceMagazine , a mammoth effort exploring how JAK inhibition modulates checkpoint immunotherapy responses! congratulations Divij!!! science.org/doi/10.1126/scie…
so excited to see this story from the amazing @ScientistBecs and @SunLab_Official out this week! super cool data on how dietary restriction can modulate NK cell function and cancer immunity, massive congratulations to my 🇦🇺 sci-sister Bec! 🙌💫🍾 you are awesome!
Thrilled to have this story out online @ImmunityCP!! Together with @SunLab_Official, we highlight how dietary fasting improves NK cell anti-tumor immunity and examine the tissue-specific processes that drive these improved responses 🧵cell.com/immunity/fulltext/S…
thank you for featuring our study on the Doherty Podcast this week @TheDohertyInst ! was great to talk science 🤓🧬👩🔬 follow the link below to listen!!
📣New podcast episode has dropped! 'Autoimmune skin conditions could be treated by targeting T cells' with @simpak
🎧Find us wherever you listen to your podcasts or via our website: doherty.edu.au/news-events/p…
@UniMelbMDHS @TheRMH @LMackayLab
Simone Park retweeted
🌟Excited to share our latest work on how functionally distinct skin TRM utilise different pathways to establish residency, published today in @ScienceMagazine! A true labour of love by BFF @simpak and @susanna_c_! 👩🔬 @TheDohertyInst @UniMelb @UniMelbMDHS science.org/doi/10.1126/scie…
thank you also to @theheraldsun heraldsun.com.au/lifestyle/h… and @RNBreakfast abc.net.au/listen/programs/r… for spotlighting our work yesterday! 🌟🫶
🙌 @susanna_c_ explaining the implications of our research to @7NewsMelbourne yesterday!
Melbourne researchers have made breakthrough discoveries that may help those suffering from skin conditions such as psoriasis. They found new molecules that control disease-causing immune cells in the skin and can be targeted without impacting the barrier that fights off cancer. To discuss, @Rebecca7Maddern spoke with Dr @susanna_c_ from @TheDohertyInst. 7NEWS.com.au #7NEWS
Top of the list on my thank-you's is the one and only brilliant @susanna_c_- not everyone gets to experience the happiness of sharing a co-first author paper with their best friend, and I feel incredibly lucky to do it with you 🌟🌟
And last but not least: to @LMackayLab herself -- for pitching me this project when I was bored of measuring tumors, all your support, and for taking this science all the way to the finish line with me. We finally made it! 💫🏆
