Rama Sekhar (@vcrama) header
Rama Sekhar (@vcrama) profile picture

Partner @MenloVentures. Cyber and AI infra VC, wine nerd, and extremely amateur hoops player. #vc #startups, die hard @Giants fan, @RutgersU, @Wharton

San Francisco, CA
Joined June 2011
Photo by Rama Sekhar (@vcrama)Photo by Rama Sekhar (@vcrama)Photo by Rama Sekhar (@vcrama)Photo by Rama Sekhar (@vcrama)Photo by Rama Sekhar (@vcrama)Photo by Rama Sekhar (@vcrama)Photo by Rama Sekhar (@vcrama)Photo by Rama Sekhar (@vcrama)Photo by Rama Sekhar (@vcrama)Photo by Rama Sekhar (@vcrama)
Menlo is excited to welcome @brielee_lu to the team as our newest investor! Brie is focused on early-stage investments across AI, physical infrastructure (power, defense, autonomy), and the software on top of it. She believes that the best early-stage companies are often undefinable and wants to support exceptional people wherever they’re headed. More on Brie and her focus areas here: menlovc.com/team/brie-lu/
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Grab a cup of coffee and check out the @MenloVentures 2026 State of Enterprise AI report! Enterprise AI spend is skyrocketing and agentic token usage has overtaken human usage.
This just in: Menlo Ventures’ 2026 The State of Enterprise AI report is live. In 2026, enterprise AI spend skyrocketed 5.4x from $33B to $177B in a single year. The full report covers how AI became an economy-scale force this year, and shows where the dollars are going, which markets are working, and which models buyers choose. More from @timt, @mejoff, @deedydas, and @derekgxiao: mnlo.vc/enterprise-ai-26
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here's to 50 years!
Replying to @MenloVentures
@MenloVentures just turned 50. What a difference half a century can make! Apple II (1977): First mass-market personal computer TCP/IP adopted on ARPANET (1983): Foundation of the internet Macintosh (1984): Mainstream graphical interface Cisco, Sun, Novell (1984): Networking and client-server spread Gilead (1987): Anti-viral drugs, founded at Menlo Digital cellular (1991): Mobile phones go mass-market Linux (1991): Open-source OS World Wide Web (1991): Berners-Lee's public release Mosaic browser (1993): Web becomes usable by everyone Netscape IPO, Amazon, eBay (1995): Kicks off the dot-com boom Google (1998): Search organizes the web BlackBerry (1999): mobile email Napster (1999): Digital music, a preview of streaming disruption iPod/iTunes (2001-03): Digital media distribution Facebook (2004): Social networks go mainstream YouTube (2005): User-generated video AWS (2006): Cloud computing iPhone (2007): Modern smartphone Siri (2008): First viable AI agent Roku (2008): Streaming TV box with one “channel”, Netflix Bitcoin (2009): Cryptocurrency and blockchain Uber, Airbnb, Instagram (2009-10): Mobile-native marketplaces & social AlexNet (2012): Deep learning takes off CRISPR gene editing (2012): Programmable biology Chime (2013): consumer banking funded by interchange vs. fees Transformers paper (2017): Architecture behind modern AI mRNA COVID vaccines (2020): Rapid biotech platform proof GPT-3 (2020): Large language models show broad capability Anthropic (2021): Dario and team leave OpenAI to build a safety-centric LLM ChatGPT (2022): AI reaches mass consumer adoption Generative AI and agents (2023): Models that write code, create media, and take actions Claude Code (2025): turning point of machine vs. woman writing software Hard to imagine what the next 50 might bring!
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Thanks to @matanSF and the entire @FactoryAI team for partnering with us. And yes, @mmurph is the real deal!! 🚀🚀🚀
Matt Murphy is a legendary investor with a track record of being very early and being very right. He led the Series D of Anthropic in Jan 2024. Their best model was Claude 2.1. I am thrilled to have @mmurph and Menlo Ventures investing in @FactoryAI. We are still so early.
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Welcome @BoleaJuliette to @MenloVentures !
Menlo is excited to welcome @BoleaJuliette to the team as our newest principal! Juliette is focused on early-stage investments across consumer and AI-native applications, working closely with founders to articulate why their products matter and translate that into effective GTM strategies. More on how Juliette works with founders here: menlovc.com/team/juliette-bo…
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Are you an AI power user? See how you stack up against my favorite stat from today’s @MenloVentures State of Consumer AI Report: Nearly a quarter (24%) of AI users spend more than an hour a day with AI, and 10% spend more than two. @shawnvc @amywumartin @samanthasborja
Menlo’s 2026 State of Consumer AI report is here.  The headline: adoption barely moved this year, but global spend tripled to $40B and existing users went deeper. 55% of AI users now pay for at least one product 25% of Americans use AI every day The story isn't how many people have tried AI. It's what happens as the relationship deepens across time, money, tasks, and autonomy. Full report from @shawnvc, @amywumartin and @samanthasborja here: mnlo.vc/ConsumerAI_26
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Congrats to @openrouter on joining @stripe! OpenRouter is the “transfer switch” of AI, just as Stripe became the switch for payment processing. Kudos to my @MenloVentures partners @mmurph and @deedydas on seeing this early!
Replying to @deedydas
loved partnering with you and our bud @AnjneyMidha on this one! 🙏
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As AI collapses the cost of building, one-person companies become inevitable. You can see that shift in our investments--with TEN Menlo portfolio companies named to @notablecap's Prosumer AI 40. Congrats to the teams at @askalphaxiv @AnthropicAI @CompositeAI @florafaunaai @higgsfield @Lovable @openevidence @suno_ai_ @WisprFlow --recognized for expanding what one person can actually accomplish. notablecap.com/prosumer-ai-4…
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I’d say welcome back but he never left! Congratulations @dougleone on returning as Chairman of @sequoia. Here’s to backing more iconic companies like @Zafran_io 🥂@sanazyashar
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Great roster of @MenloVentures portfolio companies in the @Wing_VC and @EricNewcomer 2026 Enterprise Tech 30 list!
Incredible to see so many Menlo-backed companies on @Wing_VC and @EricNewcomer's 2026 Enterprise Tech 30 list! Congrats to @AnthropicAI, @AbnormalAI, @cursor_ai, @databricks, @WeAreLegora, @Lovable, @openevidence, @OpenRouter and @WisprFlow 🎉 See the full list: wing.vc/et30#ET30
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Rama Sekhar retweeted
👀 Amazing progress at @AnthropicAI : $14B run rate, growing >10x y/y every year since launch. Thrilled to have doubled down in this $30B round and every round since we first invested, making this @MenloVentures largest investment by far in our 50 year history! p.s., this is what enterprise AI leadership looks like! 👇👏🚀
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Rama Sekhar retweeted
18 years ago today, Eli Manning and the Giants defeated the Patriots in Super Bowl XLII. 18 wins and 1 Giant loss.
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Rama Sekhar retweeted
There's been a lot of interest recently in @MenloVentures's 2025 Enterprise AI report! We started publishing this report in 2023 to put real numbers behind how enterprise adoption of generative AI was actually evolving. Three years in, we've captured just how quickly the market has accelerated -- growing to $37B+ this year -- as well as @AnthropicAI's growing presence in the enterprise. The full methodology is in the report (just scroll to the bottom!) but wanted to share more about who we talked to for this report. We worked with a third-party research firm to survey nearly 500 execs actively buying and building with AI, ranging from Fortune 500 financial institutions to high-growth AI-native startups Of the builders: - 334 surveyed used a model API - 34% CIO / CTO / CEO - 47% in companies of 1K+ FTEs - 61% in tech - 42% IT / 24% product & engineering Respondents didn't know Menlo commissioned the study and none came from our network
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📣Funding announcement! @MenloVentures is thrilled to team up with @tweetsbycolin, @bsinthewild, and the entire @clerk team to deliver developers the best agent identity, auth, and user management solution in the world! More here: menlovc.com/perspective/for-…
We raised a $50m Series C from @MenloVentures and @AnthropicAI's Anthology Fund AI has presented an exciting new challenge in authentication: Agent Identity We'll be tackling it head-on, alongside continued innovation in our authentication, multi-tenancy, and billing products.
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congrats @derekgxiao !
We're thrilled to announce @derekgxiao's promotion to Principal! 🎉 Since 2022, he's helped drive marquee investments in Anthropic, Neon (acquired by Databricks), and Unstructured while co-authoring our State of GenAI reports. Derek brings deep technical insights to founders at the frontier. Congratulations, @derekgxiao!🚀
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Congrats @nikitabase and my partner @timt as @MenloVentures portfolio company @neondatabase joins forces with @databricks !
I’m excited to share a major milestone: Neon is joining forces with @databricks. neon.tech/blog/neon-and-data… Together, we will build the best Postgres experience in the world and one of the most important pieces of the modern AI-native stack. Day 1 again for @neondatabase
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Rama Sekhar retweeted
Introducing Clerk Billing The easiest subscription billing for B2B and B2C SaaS. No webhooks, no UI to build, no payment integration code, no DIY authorization engine. Just enable Billing and drop a <PricingTable/> on your /pricing page!
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Had a blast chatting about Security for AI and AI for Security with @MichaelNovinson at RSA!
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