Physician-scientist interested in the Heart, Stem Cells, CRISPR, CHIP, and Cardio-oncology @cityofhope
Joined November 2017
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June Rhee retweeted
Colchicine reduces competitive advantage of clonal hematopoiesis (esp TET2) in COLCOT ahajournals.org/doi/abs/10.1… @CircAHA
Similar to LoDoCo2 jacc.org/doi/10.1016/j.jacc.… @JACCJournals
Our prior work in mice & human biobanks suggests that colchicine may be effective in reducing TET2 CHIP-associated CVD risk academic.oup.com/eurheartj/a… @ESC_Journals
June Rhee retweeted
It was an honor to be a part of this fantastic podcast series. You’re a gifted interviewer who leads by example. @cityofhope and the countless mentees you’ve influenced are fortunate to have you.
A touching conversation with @ArmenianSaro, our Chair of #PediatricOncology, on the @cityofhope podcats. Despite years of knowing him, had no idea the personal connection he had to the field.
Listen here:
podcasts.apple.com/us/podcas…
June Rhee retweeted
In this exploratory analysis, Tx w/ low-dose colchicine was assoc w/ an attenuated annual clonal growth in TET2 CH. Findings suggest potential for colchicine to curb proliferative advantage of key CH driver mutations jacc.org/doi/10.1016/j.jacc.…
#ESCCongress #WCCardio #JACC @mchonig
June Rhee retweeted
A true legend in the field of hematology/oncology. Dr. Stephen Forman was involved in the seminal studies of BMT for hematologic malignancies & evolved into a pioneer of CAR-T cell therapy. There are literally dozens of faculty at @cityofhope & beyond who consider him to be their most influential mentor. This podcast is a must-listen! @TDorffOnc @SaulPriceman @ArmenianSaro @stacywgray
Could radiation be the key to unlocking CAR T cell therapy’s full potential? On the new episode of On the Edge of Breakthrough: Voices of Cancer Research (w/ @montypal), Dr. Forman breaks down how combining radiation with CAR T could enhance impact. Full episode coming 7/22.
June Rhee retweeted
Germline genetic variation has been linked to both hematologic cancer and clonal hematopoiesis. But does germline variation influence the likelihood of CH progressing to cancer? And if so, why? We tackle these questions here in @NatureGenet
nature.com/articles/s41588-0…
June Rhee retweeted
Also deeply thankful to @AlexBickMDPhD, @pnatarajanmd, @jrblundell, @nilanjan10c, @carolinewatson, @hamish_macg, @DrFlashHeart, @yincaoScD, @bloodgenes, and many others for their incredible collaboration and support!
Please see the full author list here 👇
June Rhee retweeted
We’re honored to welcome world-renowned microbiome expert Kenya Honda, M.D., Ph.D. and his research team, to @cityofhope. In partnership with @KeioGlobal, this global collaboration will advance microbiome science and speed breakthroughs in immune-based therapies.
June Rhee retweeted
🚨 New paper in @NatureGenet !
How does cancer chemotherapy reshape the HSC landscape and drive the evolution of therapy-related myeloid neoplasms? We uncovered this process through single-colony WGS! See the full paper here! nature.com/articles/s41588-0…
June Rhee retweeted
For all your BCVS related news, check out the latest Basic Beat newsletter that should have arrived in your inbox this week. If not, this is your sign to sign up for an AHA membership and to select BCVS as your council of choice!
June Rhee retweeted
We're pleased to see our work on vascularized cardiac & liver organoids published in @ScienceMagazine.
Congrats to @oscarabilez @firstage5 and co-authors.
@StanfordCVI @StanfordMed @StanfordDeptMed @Stanford_ChEMH @GreenstoneBio
pubmed-ncbi-nlm-nih-gov.lane…
med.stanford.edu/news/all-ne…
June Rhee retweeted
EPI-Clone is a transgene-free lineage tracing method that uses single-cell DNA methylation analysis to track hematopoietic stem cell clones over time #NBThighlight nature.com/articles/s41586-0…
June Rhee retweeted
Are you ready to electrify the stage at this year’s #BCVS25 Council Dinner in Baltimore?
Whether you sing, dance, or beyond, we want YOU!
🗓️ Friday, July 25th @ 7 PM ET
📍 BCVS Scientific Sessions | Baltimore, MD
🧠 Show us your “other” side—off the lab bench!
June Rhee retweeted
For patients with lymphoma that relapses after CAR T, clinical options become vanishingly few. Now, a new study in @NEJM led by @carlhjune, Director of the PICI Center @PennMedicine, offers a new approach: huCART19-IL18 –– an IL-18–secreting, “armored” CAR T-cell.
nejm.org/doi/full/10.1056/NE…
#CARTcell #Immunotherapy #Lymphoma
June Rhee retweeted
🚨 Calling all #EarlyCareer scientists!
🔬 Want to dive into cutting-edge –omics research?
Join top experts from @UCSanDiego, @UWMadison, @UIowa, @CedarsSinai + more!
🗓️ Wed, May 7 | 3–4:15pm EST
🎟️ Free with AHA membership
👉 bit.ly/BCVSEC
#CardioTwitter @AHAScience
June Rhee retweeted
NEJM@NEJM
24 Apr 2025United States
United StatesConnected via United States App StoreAccount-level information, not a live location or per-post device.
Both clonal hematopoiesis of indeterminate potential (CHIP) and cancer are more common with age. When they coexist in the same patient, CHIP cells may migrate to the tumor and have an adverse effect on overall survival. Full study results: nej.md/3EnzMVu
Editorial: Clonal Hematopoiesis as a Driver of Solid Tumors nej.md/42sTdWh
ALT A schematic representation of clonal hematopoiesis of indeterminate potential (CHIP) and tumor-infiltrating clonal hematopoiesis (TI-CH) in a patient with lung cancer.
June Rhee retweeted
Best talk I have been to all year was right here at @cityofhope at our GU retreat (organized by @arafflemd). @yunroseli @COH_RadOnc just delivered a tour de force highlighting her work in #prostatecancer w @TDorffOnc et al focused on fasting interventions & other metabolic strategies. Well executed @NIH funded studies w rich correlatives; recently funded effort looking at #GLP1 alongside @JuneWRhee thanks for a massive @American_Heart grant. Keep up the amazing work, Rose! Proud of you.
June Rhee retweeted
A high polygenic risk score (PRS) for screening prostate cancer was superior to a PSA test or MRI for detecting clinically significant disease (Gleason ≥7). A big step forward for supporting utility of PRS @NEJM
nejm.org/doi/full/10.1056/NE…
June Rhee retweeted
In patients with #lymphoma undergoing autologous HCT, #CHIP is highly prevalent and associated with significantly increased risk for HF as well as NRM. Further studies are warranted jacc.org/doi/10.1016/j.jacca…
#JACCCardioOnc #CardioOnc #lymsm #HeartFailure
