Peter Kunach (@KunachP) header
Peter Kunach (@KunachP) profile picture

Peter Kunach

@KunachP
 Montréal, Québec
Joined June 2021
  • Tweets54
  • Following148
  • Followers105
This is an absolute BEAST of a paper from one of the most rigorous scientists I know @JVaquerAlicea …really elevates past work on tau biosensors to another level: the power of simple cell models in action! Congratulations to Jaime, @MDiamond_Lab et al. biorxiv.org/content/10.1101/…
Functional classification of tauopathy strains reveals the role of protofilament core residues

Functional classification of tauopathy strains reveals the role of protofilament core residues

Distinct tau amyloid assemblies underlie diverse tauopathies but defy rapid classification. Cell and animal experiments indicate tau functions as a prion, as different strains propagated in cells...

biorxiv.org
13
53
4,168
Peter Kunach retweeted
Amit Kumar (@AKumar_KI) profile picture
Amit Kumar@AKumar_KI25 Mar 2024
Mark your calendar for this next IDCS talk by Prof. Clifford Jack! @CAR_Karolinska @MayoClinic @andreia_rocha_ @KunachP @pedrorosaneto @erzimmer @M_Malpetti @MCSA_Montreal
International Dementia Conference Series (@_IDCS_) profile pictureInternational Dementia Conference Series@_IDCS_24 Mar 2024
🚨 Save the date! Zoom link: mcgill.zoom.us/j/3505997027 Register at: i-dcs.org/contact Sponsored by @_BrightFocus
Image from International Dementia Conference Series (@_IDCS_)
3
16
1,068
📌Don't miss! This Wednesday! Prof. Cynthia Lemere! Zoom link: mcgill.zoom.us/j/3505997027 or Register at: i-dcs.org/contact @pedrorosaneto @erzimmer @andreia_rocha_ @AKumar_KI @KunachP @M_Malpetti Sponsored by @_BrightFocus
Image from International Dementia Conference Series (@_IDCS_)
9
1
14
2,007
Like CTE and SSPE, ALS/PDC has also the CTE tau fold. With special thanks to @qichao8886, Bert M. Verheijen, Yasumasa Kokubo and @sy31802. As always, with @SjorsScheres. pnas.org/doi/10.1073/pnas.23…
Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold |...

Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold |...

The amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS/PDC) of the island of Guam and the Kii peninsula of Japan is a fatal neurodege...

pnas.org
17
1
49
13,144
Who could be better to talk about Amyloid-Beta? Prof. Dennis Selkoe himself today at the IDCS! Don't miss it! Zoom link: mcgill.zoom.us/j/3505997027 or register at: i-dcs.org/contact @pedrorosaneto @erzimmer @AKumar_KI @KunachP @M_Malpetti Sponsored by @_BrightFocus
Image from International Dementia Conference Series (@_IDCS_)
5
18
1,353
This week! Don't miss it! Register at act.alz.org/site/R?i=kYmjWNj… @alzassociation @ImmunityPIA @NeuroimagingPIA
Image from International Dementia Conference Series (@_IDCS_)
4
1
6
2,565
Congratulations @BShoichet and first author Matt Smith! biorxiv.org/content/10.1101/…
Docking for molecules that bind in a symmetric stack with SymDOCK

Docking for molecules that bind in a symmetric stack with SymDOCK

Discovering ligands for amyloid fibrils, such as those formed by the tau protein, is an area of much current interest. In recent structures, ligands bind in stacks in the tau fibrils to reflect the...

biorxiv.org
4
210
Peter Kunach retweeted
Alzforum (@alzforum) profile picture
Alzforum@alzforum28 Sep 2023
Cryo-EM shows Merck’s MK-6240 tau tracer cradled within each C-shaped protofilament fold of AD tau fibrils. @UTSWNews @McGillU ow.ly/JqbG50PQJVu
2
14
2,029
MK-6240 is a PET imaging agent that can discern subtle early-stage Alzheimer's brain changes. How does it interact with Alzheimer's tau filaments at a high-resolution molecular level? 🔬⚡Read on and check out our bioRxiv article:
8
39
2
194
45,084
Cryo-EM structure of Alzheimer disease tau filaments with PET ligand MK-6240 biorxiv.org/cgi/content/shor… #biorxiv_neursci
1
2
6
3,050
Congratulations @KunachP biorxiv.org/content/10.1101/…
Cryo-EM structure of Alzheimer’s disease tau filaments with PET ligand MK-6240

Cryo-EM structure of Alzheimer’s disease tau filaments with PET ligand MK-6240

Positron Emission Tomography (PET) ligands have advanced Alzheimer’s disease (AD) diagnosis and treatment. Using autoradiography and cryo-EM, we identified AD brain tissue with elevated tau burden,...

biorxiv.org
2
3
1
14
2,417
So proud to be part of this great initiative!
Eduardo Zimmer (@erzimmer) profile pictureEduardo Zimmer@erzimmer15 Feb 2023
The discussions at @MCSA_Montreal “International Dementia Series” are becoming mind-blowing! If you are missing, register yourself at i-dcs.org and check the recordings! Thanks for making it happen @KunachP @andreia_rocha_ @M_Malpetti and @AKumar_KI 🧠
2
21
1,758
Peter Kunach retweeted
Eduardo Zimmer (@erzimmer) profile picture
Eduardo Zimmer@erzimmer15 Feb 2023
The discussions at @MCSA_Montreal “International Dementia Series” are becoming mind-blowing! If you are missing, register yourself at i-dcs.org and check the recordings! Thanks for making it happen @KunachP @andreia_rocha_ @M_Malpetti and @AKumar_KI 🧠
2
14
1
41
5,182
📢 Join the International Dementia Conference Series this Wednesday (Feb 1) at 10am EST for an event by Prof. Henrik Zetterberg from @ucl @goteborgsuni @UKDRI " Update on biofluid-based biomarkers for neurodegenerative dementias" DM for login info!
Image from McGill Research Centre for Studies in Aging (@MCSA_Montreal)
11
1
29
2,969
📢Join the International Dementia Conference Series on Wednesday, July 13th at 10am EST for a conference by Prof. Virginia Man-Yee Lee from @Penn @PennMedicine "Amplification of Pathological Tau Strains" DM for login info! For previous lectures: i-dcs.org
Image from McGill Research Centre for Studies in Aging (@MCSA_Montreal)
4
2
9
Peter Kunach retweeted
Amit Kumar (@AKumar_KI) profile picture
Amit Kumar@AKumar_KI22 Jun 2022
📣 Time for the 2nd talk of IDCS Tau series!! Mark your calendar 🗓 😊 @CAR_Karolinska @pedrorosaneto @KunachP @andreia_rocha_ @M_Malpetti @erzimmer @MCSA_Montreal @ChariteBerlin @DZNE_en @DZNE_de
McGill Research Centre for Studies in Aging (@MCSA_Montreal) profile pictureMcGill Research Centre for Studies in Aging@MCSA_Montreal22 Jun 2022
The International Dementia Conference Series is honored to be hosting Dr. Susanne Wegmann from @ChariteBerlin @DZNE_en @DZNE_de "Tau Protein Condensation: Implications for Neuronal Function and Disease" DM for login info! For previous lectures: i-dcs.org
Image from McGill Research Centre for Studies in Aging (@MCSA_Montreal)
3
1
11
📢SPECIAL EVENT📢 The International Dementia Conference Series is honored to be hosting Prof. Khalid Iqbal from the New York State Institute for Basic Research for his event "Tau: Why, What, and How?" DM for login info For previous lectures: i-dcs.org
Image from McGill Research Centre for Studies in Aging (@MCSA_Montreal)
4
2
8
Peter Kunach retweeted
Amit Kumar (@AKumar_KI) profile picture
Amit Kumar@AKumar_KI8 Jun 2022
📣 Don’t miss the opening keynote lecture of our new IDCS series on Tau Protein! @andreia_rocha_ @M_Malpetti @KunachP @erzimmer @pedrorosaneto @CAR_Karolinska @MCSA_Montreal @IgorCamargoF
McGill Research Centre for Studies in Aging (@MCSA_Montreal) profile pictureMcGill Research Centre for Studies in Aging@MCSA_Montreal7 Jun 2022
📢SPECIAL EVENT📢 The International Dementia Conference Series is honored to be hosting Prof. Khalid Iqbal from the New York State Institute for Basic Research for his event "Tau: Why, What, and How?" DM for login info For previous lectures: i-dcs.org
Image from McGill Research Centre for Studies in Aging (@MCSA_Montreal)
9
1
14
Peter Kunach retweeted
Amit Kumar (@AKumar_KI) profile picture
Amit Kumar@AKumar_KI18 May 2022
No Figure Legend needed! 😎 Looking forward to our next IDCS series on ‘Tau’! Thank you everyone for your excellent support 🙌🏻 See you @andreia_rocha_ @KunachP @erzimmer @pedrorosaneto @MCSA_Montreal @CAR_Karolinska @_BrightFocus @alzassociation @IgorCamargoF @MonaLisaMalarte
Image from Amit Kumar (@AKumar_KI)
1
4
1
14
My face this morning at #IDCS when Dr @MaluTansey presented data showing that TNF levels start increasing around 30 years and I remembered I am 30, ahahahahahah! Suuuch an amazing talk! Thaaaank you! The take home message for us students: Choose your mentor wisely!
Image from Andreia Rocha (@andreia_rocha_)
1
6
18
Load more