Marc Alard Morgan retweeted
How did the chromatin field get to the here-and-now ? A sweeping historical perspective of the intersections between technology and biology from our very own Ellen Weinzapfel ! #epicypher #chromatin
doi.org/10.1042/BCJ20230342
Marc Alard Morgan retweeted
Fantastic collaboration with the Musselman lab that shows why those pesky histone PTMs don't always appear to play together : been looking in the wrong place / way : Nucleosomes don't just CARRY the tails - they regulate their use ...
Pleased to share this collab with @MusselmanLab using BPTF to show how nucleosome context shapes combinatorial #chromatin interactions. Together these results support a redefining of the "histone code" using nucleosome substrates.
hubs.la/Q02k9WMH0
Marc Alard Morgan retweeted
Sharing @ScienceAdvances identification of first RNAPII elongation factor repeat unit ELOA3 gene cluster conserved among primates & regulates pause release. Congratulations Marc & Saeid & thank you @EichlerLab @NU_BMG_SQE @NUFeinbergMed @ScienceMagazine bit.ly/3MSYiP6
A Postdoc at St. Jude was senselessly murdered during a robbery. A Gofundme has been started to support his wife and child during this impossibly difficult time.
gofund.me/4fd2017a
Marc Alard Morgan retweeted
Excited to share my first ever paper containing part of my PhD work! If you're interested in Eomes, the Tbox family, and degrons in vivo, give it a read. Μany thanks to current and past Robertson lab members, esp my co-1st authors @ItaCostello and Marilena pnas.org/doi/10.1073/pnas.23…
Very interesting paper linking 3D chromatin folding to allelic imprinting
genesdev.cshlp.org/content/e…
Marc Alard Morgan retweeted
I'm delighted to release the first half of my new open-access online textbook in human population genetics:
web.stanford.edu/group/pritc…
Marc Alard Morgan retweeted
Three of the more costly and frequently used reagents in molecular biology are rolling circle amplification (RCA) mix, chemically competent MachOne (or other E. coli) cells, and Gibson assembly mix. Postdoc Julian Willis—who is starting his own lab in the UK soon—developed homemade recipes for each that reduce costs ~3x (or more at large-scale). Links to each recipe:
RCA mix:
docs.google.com/spreadsheets…
Chemically competent MachOne cells:
docs.google.com/spreadsheets…
Gibson assembly mix:
docs.google.com/spreadsheets…
Marc Alard Morgan retweeted
@BiochemOxford are recruiting a new Associate Professor. Great city and wonderful colleagues! Those with interests in transcription and gene regulation (either prokaryotes or eukaryotes) strongly encouraged to apply!
Please retweet!
my.corehr.com/pls/uoxrecruit…
Marc Alard Morgan retweeted
I just released version 3.1.3 for all platforms. This has a couple of bug fixes, but the big update is reading fastq files from @plasmidsaurus. The Phred data are visible in the X-ray window of a fastq file.
Marc Alard Morgan retweeted
Hey, computational folks, could you RT? @DnbResearch's @AShirinifard is recruiting a Lead Computational engineer developing real-time image processing pipelines for advanced #microscopy initiatives One of a kind opportunity, challenges and colleagues URL: talent.stjude.org/careers/jo…
Marc Alard Morgan retweeted
What to use my scripts for gene co-expression analysis or generate nice graphics, but no experience with R? Don't worry, I have you covered! I have separate "Online_R_learning" tutorial on GitHub. It has 14 lessons, but really just the first 5 will get you a long way.
Marc Alard Morgan retweeted
Brain cells connect with each other while a single neuron stays alone:
#biology by A. Bahnson
Marc Alard Morgan retweeted
Congratulations to all authors, but especially to Hanneke - who really drove this story from beginning to end. Fantastic to see this in print 🎉
Now out in @NatureSMB: my paper on the sequence determinants of RNAPII elongation potential! I'm so happy to see it in its final form! 🤩
Find it here: nature.com/articles/s41594-0…
Or view with this link, if you don't have a subscription: rdcu.be/cPjTJ
Marc Alard Morgan retweeted
We are looking for a (fully funded) postdoc to join our team at NIH in Bethesda Maryland (DC metro area). Evolution, genomics, retrotransposons, zinc finger genes, meiotic recombination and more.
Marc Alard Morgan retweeted
@jonathanpkarr and Jack Ferrie revisited some big questions and inconsistencies in the gene reg. field and put forth a new model for explaining enhancer-promoter communication that doesn’t require direct contact. Check out the details of the TAG model now at @GenesDev – at Albany, CA
What if enhancers worked w/o contacting promoters? What if functional PTMs were on diffusible proteins, not histones? And what if diffusion, not looping, bridged CREs to their targets?
We think it's possible. Check out our new perspective to see how: genesdev.cshlp.org/content/e…
Marc Alard Morgan retweeted
Very happy to share our recent collaboration with the Shilatifard lab & @RothbartLab led by @MarcAlardMorgan in which we dissected the binding properties of the #chromatin associated protein PHIP/BRWD2 using our dCypher nucleosome binding platform. (1/n)
genesdev.cshlp.org/content/e…
Marc Alard Morgan retweeted
In our May issue
#Review from Andrea Piunti & Ali Shilatifard discussing roles of #Polycomb repressive complexes in mammalian development and cancer
@NUFeinbergMed
#epigenetics #methylation #PRC1 #PRC2
go.nature.com/3cNTiZd
