Critical Care / Anticoagulation Clinical Pharmacy Specialist | CVICU | Inova Heart and Vascular Institute
Falls Church, VA
Joined February 2012
- Tweets194
- Following368
- Followers100
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Will we soon have safer antithrombotic options for LVAD patients? #ARIES says yes to aspirin withdrawal #DOACLVAD investigates apixaban in #HM3
Withdrawal of aspirin is safe in #LVAD patients, how about apixaban instead of warfarin?
Introducing the DOAC LVAD Study—design paper online NOW @JCardFail 👇
#ARIES #DOAC #LVAD
@PalakShahMD @MaryLoobyPharmD
@coconnormd @IHVInews
doi.org/10.1016/j.cardfail.2…
Mary Looby retweeted
Major reduction in bleeding with #ARIES trial in #LVAD pts. Now let’s improve #QOL and healthcare burden with #DOAC therapy. Read the DOAC LVAD study design paper.
@preventfailure @manreetkanwar @TomCascinoMD @rcogswell_umn @KeyurBShahRIC
A program and an RPD so good it makes me want to go back and do a PGY2 all over again !!
Interested in an ID PGY2? Join us at one of our virtual info sessions on either 11/30 or 12/14 to learn more about our ASHP accredited program at @YNHH in New Haven, CT. Register at: surveymonkey.com/r/FGJ2D2Q or via the QR code.#IDTwitter #PharmRes @omattacycline @ruxyID @abripenem
Big shoes to fill but great opportunity!
💊✨JOB ALERT ✨💊
Searching for an abdominal transplant pharmacist at Inova Fairfax in Northern VA!
💊 >120 kidney/panc txps last year
💊 Plenty of precepting
Job link: tinyurl.com/2s4f9aab
DMs are open for questions!
@accpimtrprn @AST_TXPHARMCOP #TxPharm #TwitteRx
One of the most exciting things I’ve been a part of in my career. 🤩 Cannot wait to share what we learn @IHVInews @PalakShahMD #DOACLVAD
Thrilled to announce launch of the first @IHVInews FDA IND trial, DOAC LVAD, to evaluate safety of apixaban in patients with LVADs.
Congratulations @PalakShahMD, Mary Looby and the AHF & VAD Research Teams @bradbumm
clinicaltrials.gov/ct2/show/…
Mary Looby retweeted
Just posted a photo @ Inova Fairfax Hospital instagram.com/p/CWyY1QLFW0S/…
Not to mention andexanet at 5-10x⬆️ cost vs others… with no known advantage.
🔑💭: How do DOAC reversal agents compare?
A meta-analysis from Gomez-Outes et al analyzed 4-PCC, idarucizumab & andexanet for reversal of severe bleeding associated with DOACs.
60 studies & 4735 pts:
🚫difference in mortality
↔️hemostatic efficacy
⬆️VTE with andexanet
ALT https://doi.org/10.1016/j.jacc.2021.04.061
Mary Looby retweeted
“It takes 10 years to become an overnight success.” - marathoners
“Hold my beer.” - Molly Seidel
#TeamUSA
Way to go @IanBHollis 👏🏻👏🏻. Moving in the right direction where less is more.
Happening now #ISHLT2021, UNC 90-pt study, no ASA in #LVAD patients from implant reduces hemocompatibility related adverse events. 6-fold higher risk of bleeding with ASA, no increase in stroke. @bradbumm @NirUrielMD @preventfailure @manreetkanwar @rcogswell_umn @tonkhueMdPhd
Mary Looby retweeted
Happening now #ISHLT2021, UNC 90-pt study, no ASA in #LVAD patients from implant reduces hemocompatibility related adverse events. 6-fold higher risk of bleeding with ASA, no increase in stroke. @bradbumm @NirUrielMD @preventfailure @manreetkanwar @rcogswell_umn @tonkhueMdPhd
Great resource for learners of all disciplines.
📄🤓👾💊🦠🔬📖
Updated my antibiotic cheat sheet to being a “bugs & drugs cheat sheet”
📲 LearnAntibiotics.com
💬 Any suggestions for additional updates are 😃 welcomed. #IDtwitter #TwitteRx
Upstream Xa inhibition preventing thrombin generation proving to be 🔑... dabig failed in VADs and mechanical valves (RE-ALIGN). More potential for Xa inhibitors based on case series in VADs and ongoing PROACT Xa (apix w/ On-X valve). Can we ⬇️ GIB in VADs with this approach?🤞🤞
The German study used dabigatran which is a direct thrombin inhibitor and showed harm. Apixaban works through a different pathway (Xa inhibitor), which is more important in VADs. @bradbumm ahajournals.org/doi/10.1161/…
In the NEJM article they state low dose heparin (LMWH) DECREASED platelet activation and that PF4 activation was independent of heparin. I’m puzzled by why the authors concluded heparin can’t be used. No SRA to corroborate a functional heparin rxn.
I’m addition to a similar clinical picture, patients w/VITT post @AstraZeneca demonstrated PF4 heparin antibodies.
It is extremely important to differentiate this from other thrombosis as heparin should NOT be used in these patients.
5/x
Yessss. Felt like we were in a tough spot with RED VELVT signaling we need to use VKA for LVT. Great to have a controlled trial to clarify/correct this. 👏🏻
Happy to share the results of No-LVT @JACCJournals
-79 patients with left ventricular thrombi were randomized to rivaroxaban vs warfarin
-Rivaroxaban was non-inferior and had faster thrombus resolution in comparison to warfarin.
@EchofirstB
jacc.org/doi/10.1016/j.jacc.…
@InovaCareers @IHVInews @InovaHealth is looking for cardiology trained pharmacists to join our established cardiac critical pharmacy team! We've got it all.... cardiogenic shock, HF, durable and temp MCS, PH, txp, and expanding pharmacist-run clinics for endless opportunities.
Not to mention the most supportive team a pharmacist could ask for @mpsotka @ShashankSinhaMD @cmrosner @FinniganApril @jennasmithrx @AirInBags @ErikOsborn77
Ahhh how did I leave off my old friend and favorite HF cardiologist @PalakShahMD ... newly connected in the twitterverse
Try to watch and not smile. Impossible. 😍
❄️🐼 Slides, somersaults and pure panda joy. Happy snow day from giant pandas Mei Xiang and Tian Tian! 🌨🐾
. . .
#SnowDay #PandaStory
Such a great leader and advocate in cardiac surgery and beyond. I’m fortunate to have had the opportunity to learn from him for the past 9 years. Well deserved👏🏻👏🏻👏🏻
Proud of @IHVInews Cardiothoracic Surgery Director, Dr. Alan Speir, recipient of the @STS_CTsurgery #STS2021 Distinguished Service Award in recognition of his outstanding contributions to cardiothoracic surgery and to the society @InovaHealth @coconnormd bit.ly/3puxHKE
