Pharmacology graduate student @UNC in the Palmer lab studying curative chemotherapy combinations
Joined August 2020
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Sarah Patterson retweeted
I remember a long-ago @FDAOncology meeting with a small company developing an MDS drug. The company was convinced their drug was synergistic with HMAs & kept saying “we’re 2+2=5.” Finally an FDA official said they were perfectly happy for 2+2 to equal 4, if 4 was safe patients.
Sarah Patterson retweeted
You don’t need ‘1+1 makes 3’ if you can have ‘5+5 makes 10’ - @ac_palmer
@NatureCancer @SC_Patterson @PlanaDeborah @DrTonyLetai @DavidSteensma
oncodaily.com/21728.html
#Cancer #FDAOncology #HypomethylatingAgents #HMAs #NatureCancer #OncoDaily #Oncology
Sarah Patterson retweeted
New paper:
Most approved drug combinations for advanced cancer (1995-2020) have predictable clinical efficacy, because they have additive effect on Progression-Free Survival times.
In @NatureCancer at rdcu.be/drhs0
by @HaeunHwangbo @SC_Patterson @PlanaDeborah
1/6
Sarah Patterson retweeted
I hope we are moving away from “maximum tolerated dose” in oncology. #MedTwitter
Of the studies I’ve led, the one I am most proud of is the trial that showed that LOWER dose of steroids led to better survival & lower toxicity. @TheLancetOncol
#Myeloma thelancet.com/journals/lanon…
Sarah Patterson retweeted
#SACB2022 has been a great meeting with exciting research and fun people in a beautiful location. It's been a pleasure serving on the organizing committee over the last 3+ years – at Woods Hole, MA
So proud of @HaeunHwangbo for giving a great talk on clinical drug additivity at #SACB2022!
Sarah Patterson retweeted
Thrilled (and flattered) to read this preview by one of my scientific heroes and leader in the field of drug #combinationtherapy @ac_palmer @SarahCooperUNC
Online now: Predicting in vivo activity of combination therapies from in vitro drug pairs in diverse environments dlvr.it/SYsQsl
Sarah Patterson retweeted
I am so excited to share our review of drug independence and its role in curative cancer combination therapy just published #OpenAccess in @TrendsCancer. cell.com/trends/cancer/fullt… #MathOnc #CompMed #SysBio @UNC_PHCO @ac_palmer @UNC_SOM @UNC @UNC_Lineberger (1/8)
Sarah Patterson retweeted
2 papers out!
1) Across many cancers, the clinical efficacy of combination immunotherapies is predictable from efficacy of their ingredients
clincancerres.aacrjournals.o…
2) Review - what does this mean for precision oncology?
cancerdiscovery.aacrjournals…
1/n
So proud of our postdoc @AmyEPomeroy for creating a model that can accurately predict clinical trial outcomes!
I've developed a model of combination chemotherapy and trained it on DLBCL trials. The ultimate test of my model is to predict new trial results, so I predicted the results of the POLARIX trial. Today I got to check the predictions, and they were right!
bit.ly/3yuf0MC
Sarah Patterson retweeted
I'm so excited to share the primary article from my graduate work, published today in @scisignal! I am so proud of this project and thankful for all of my coauthors including @matthewipena and @beveunc.
@CompMedUNC @UNC_BCBP @UNC_PHCO @UNC_SOM
stke.sciencemag.org/content/…
Thank you @UNC_TIBBS for hosting an ornament decorating party! Definitely brought some joy during a hard year. #TIBBSholidaze
Couldn't have said it better myself!
Sarah Patterson retweeted
Whenever my husband’s students mistakenly address him as Dr. Pomeroy, he corrects them saying “Dr. Pomeroy is my wife” #WomenInSTEM
Sarah Patterson retweeted
Congrats @Aaron_Anselmo on another NIH NOA, this time for a diversity supplement for @UNCBBSP Microbiology and Immunology grad student Jilarie Santos Santiago. Terrific news for such a fantastic student!
