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Stanford, Shriram Center
Joined December 2021
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It's a new year, it's a new account! Follow us @sattelylab.bsky.social on BlueSky. See you soon friends👋
Sattely_lab sattelylab.bsky.social retweeted
Thank you @Sattely_lab for sharing your insights on engineering of plant chemistry for plant and human health at the SB.Talk seminar 🌲🙌🏼🌟 #stanford #syntheticbiology #stanfordsb
Sattely_lab sattelylab.bsky.social retweeted
.@caseyvchan, Chemistry/Biology Interface (CBI) fellow at Sarafan ChEM-H, on learning that plants produce different compounds at each developmental stage.
@Sattely_lab
ALT What is the coolest piece of science you’ve learned about in 2024? “I’ve really enjoyed learning about the correlation of compound synthesis and developmental stages in plants. For example, Niraj Mehta in Dr. Elizabeth Sattely’s lab found that daffodils charge newly developed leaf tissue with toxic alkaloids to improve plant defenses. This work lays the groundwork for toxin production discovery in other plants.”
Sattely_lab sattelylab.bsky.social retweeted
Future science innovators, submit your abstract for the Future of Agriculture for Sustainability conference by December 30th (11:59pm MST) to join Keynote Speaker Elizabeth Sattely and other leaders. Apply now at hubs.la/Q030fXfc0. #KSFutureAg25 #plantsynbio @Sattely_lab
Great job by Conor, Jack, Chloe and Ricardo from the @Sattely_lab in collaboration with the Lange lab and @fordycelab! #plant #stanford #bioengineering
Excited to share our new preprint on the Taxol pathway!
We developed a strategy to systematically activate and identify gene sets in non-model organisms and used it to find 8 new genes in the Taxol pathway, allowing us to biosynthesize Taxol precursors de novo.
Surprisingly, this required a new protein (FoTO1) that helps the first Taxol P450 oxidase produce the correct product. more here: biorxiv.org/content/10.1101/… congrats to coauthors
@Sattely_lab
@ctliu629 @fordycelab
Congrats Hannah! Great collaboration
Delighted that our latest limonoid biosynthetic pathway work is now online @J_A_C_S !
We characterise a yield boosting ⬆️ enzyme involved in an acetyl protection/deprotection step, providing new insights into furan biosynthesis 🍋🌿
pubs.acs.org/doi/10.1021/jac…
Sattely_lab sattelylab.bsky.social retweeted
My PhD work studying the biosynthesis of medicinal natural products in plants is now published. Check it out!
Now online! A developmental gradient reveals biosynthetic pathways to eukaryotic toxins in monocot geophytes dlvr.it/TDDhQ3
Sattely_lab sattelylab.bsky.social retweeted
Dr. Beth Sattely @Sattely_lab elegantly presents the difficulties and bottlenecks in plant specialized metabolism pathway discovery and approaches we can use to mine and find fascinating non-canonical enzyme classes 🪴🧬🔍✨️
Zinc deficiency is the most abundant microdeficiency of plants globally. It affects up to 50% of all arable lands. We show that Brassicaceae plants (broccoli, radish) actively secrete peptides to increase root mass under zinc starvation. biorxiv.org/content/10.1101/…
Who's that newly polished PhD candidate? 🥳Congrats to @TLowensohn70203 passing her quals
There is something truly mesmerizing about a drop of water hanging from a plant 💚 Happy Friday everyone!
Get ready for the 2nd-year grad students Tara Lowensohn and Ryan Kong: Both just received the prestigious NSF Graduate Research Fellowship! 🥳 new.nsf.gov/funding/opportun…
Congrats to Jack and everyone involved! 🌿😍
Excited to share my paper @NatureComms on the Taxol biosynthesis @Sattely_lab with some help from the @Keasling_Lab 🥳 🎉
Really happy to have contributed to the studies of this amazing molecule 😊
nature.com/articles/s41467-0… (1/2)
Sattely_lab sattelylab.bsky.social retweeted
Purifying heterogeneously expressed compound from Nicotiana extract 🌿 all the chlorophylls/pigments always make this a satisfying process 🌈
@Sattely_lab
Sattely_lab sattelylab.bsky.social retweeted
Another Taxol biosynthesis paper @ScienceMagazine science.org/doi/10.1126/scie… My wholehearted congrats to all authors! The discovery of the oxetenase is truly amazing and would greatly facilitate our work. (1/3)
Sattely_lab sattelylab.bsky.social retweeted
Now with a News & Views: "Assembling neuroactive alkaloids" rdcu.be/dtpCE
The Lycopodium alkaloids represent a valuable source of neuroactive compounds. The biosynthesis of these specialized metabolites is now shown to involve three α-carbonic anhydrase-like enzymes...
Nature research paper: Plant carbonic anhydrase-like enzymes in neuroactive alkaloid biosynthesis go.nature.com/47HvTDZ
Sattely_lab sattelylab.bsky.social retweeted
Thank you to Professor Ushimaru and Professor Abe for the excellent write up on our recent manuscript on Lycopodium alkaloid biosynthesis!
rdcu.be/dtiPg