@Schultz_Lab
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Assistant Professor of Psychiatry, Neurology, and Pharmacy Practice at the University of Iowa Carver College of Medicine
Iowa City, IA
Joined September 2011
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Jordan Schultz retweeted
A well-studied, widely used class of drugs for heart health may have benefits for Huntington’s disease. A new paper associated beta-blocker use with delayed onset and slower disease progression. Should you ask your doctor for a new prescription? #cure
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Jordan Schultz retweeted
Beta blockers may delay symptom onset and slow #HuntingtonsDisease progression. The new study results “provide hope that there may be novel targets, such as the autonomic nervous system, for modifying the disease course,” says Jordan Schultz, PharmD spr.ly/6016QHYb4
Jordan Schultz retweeted
β-blocker therapy in Huntington disease (HD) was associated with a later age at onset and a slower rate of worsening of clinical symptoms.
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We are excited to share some exciting findings just published in @JAMANeuro!
β-Blocker Use and Delayed Onset and Progression of Huntington Disease jamanetwork.com/journals/jam…
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We investigated beta-blockers based on previous findings showing that patients with HD have autonomic dysfunction. These findings provide early evidence that the autonomic nervous system may be a novel therapeutic target for slowing the progression of HD.
We thank CHDI, Inc for their support of the Enroll-HD Platform and especially all of the patients, participants, and caregivers who make this work possible!
@HarshmanLyndsay @AmyOstrem @PNopoulos @UIowaNeuro @UIowaPsychiatry @UIPharmacy @IowaMed
Jordan Schultz retweeted
Unravelling the role of huntingtin: from neurodevelopment to neurodegeneration
New scientific commentary by Jordan Schultz, Mohit Neema & Peg Nopoulos tinyurl.com/59emxnff
Jordan Schultz retweeted
More data on α1-adrenergic receptor antagonist Terazosin from @MatthewWeberPhD @narayananlab & colleagues - rodents with VTA dopamine depletion had higher interval timing variability, improved by daily terazosin; Plus more epidemiological #Parkinsons data
nature.com/articles/s41531-0…
While a diagnosis of Marfan Syndrome has not yet been confirmed, this is a tragic reminder of how important an early diagnosis can be. For my 2 yo son, @UIchildrens turned a routine eye appointment into a life-saving early diagnosis of MFS, for which I am forever grateful.
Breaking News: Grant Wahl, the celebrated soccer journalist who died suddenly at the World Cup in Qatar, suffered an aortic aneurysm, his wife said, citing an autopsy.
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Check out our most recent paper in @MDJ_Journal where we report some of the first longitudinal neuroimaging data from kids with Juvenile-Onset Huntington's Disease!
movementdisorders.onlinelibr…
This study was led by @PNopoulos @JoHD_Iowa @kids_hd and was the result of significant collaboration amongst members of @UIowaPsychiatry and @UIowaNeuro and enormous support from several dedicated people and groups, including @HDSA, @HDYOFeed, @WeHaveAFace, and @Help4HDI.
Very pleased to have results from my @ICTSIowa KL2 project published! Great to be able to have multidisciplinary collaborators @boeslab and @HarshmanLyndsay from @UIowaPeds and @UIowaNeuro!
Schultz et al. report that autonomic dysfunction in patients with presymptomatic #HuntingtonsDisease is associated with decreased functional connectivity within the Central Autonomic Network. @Schultz_lab bit.ly/3EYasmy
Our newest paper in @MDJ_Journal shows that children with long CAG repeats (>50) who were far from their predicted motor onset of HD had striatal hypertrophy that preceded degeneration. @ChANGE_HDstudy @JoHD_Iowa @UIowaPsychiatry @UIowaNeuro
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