Many thanks to @zhou_jingtian, May Wu, @Jesse_R_Dixon & the entire @salkinstitute team! Even before publication, Nathan Zemke (UCSD/Ren lab) et al. used the methylation data to ID a yoke sac to monocyte microglial switch in the aging hippocampus also out today in the @4DN package
Your DNA is like the same instruction manual in every cell of your body. So why does one cell become a brain cell while another becomes a heart cell?
The answer lies in epigenetics—the systems that tell cells which instructions to use and which to ignore.
Salk scientists, along with collaborators, created the first body-wide atlas, profiling 86,689 cells across 16 human tissues, that maps both how DNA folds and how it's chemically tagged in the same individual cells. The result is an unprecedented look at how our cells are programmed and why disease risk may differ from one cell type to another.
The freely available resource could accelerate research into conditions like schizophrenia, bipolar disorder, atrial fibrillation, and diabetes, and help train future AI tools for genetics.
Read more: salk.edu/news-release/two-wa…
Photo of Salk scientists from left to right: Jingtian Zhou, Jesse Dixon, and Joe Ecker.
@ScienceMagazine @NIHgov #4DNConsortium @UCSanDiego @AAAS
Hailing Jin retweeted
With new law, European Union can more quickly greenlight gene-edited crops science.org/content/article/…
Big congratulations again🎉🎉🎉very well deserved!
🎉Congrats to Eckerlab alumni José Alonso @AlonsoStepanova @NCState & Bob Schmitz @Schmitz_Lab @universityofga on their election to @theNASciences today! Working with you both at @salkinstitute was a true privilege - this honor is so well deserved. So proud! 🌟#NAS163 #NASmembers
I am really honored and humbled by this special recognition!
Congratulations Hailing Jin of @UCRiverside, newly inducted #NASmember! #NAS163 #microbiology #plantbiology
Thank you very much for having me and it’s my great honor to be the Varner lecturer! I am very impressed by the work you and your colleagues in the department are doing!
Great pleasure to host Hailing @hailingj1 for our Varner Lecture! Really inspiring talk on cross-kingdom RNA communication and its applications, plus tons of fun discussion.
Hailing Jin retweeted
Today in @Nature we report a new prime editing strategy that can rescue a common cause of many genetic diseases in a disease-agnostic manner. This approach converts a redundant endogenous tRNA into an optimized suppressor tRNA, enabling a single prime edit to rescue premature stop codons across different diseases.
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drive.google.com/file/d/1bSv…
Hailing Jin retweeted
Our new discovery that bacteria utilize extracellular vesicles to deliver RNAs into fungi substantially broadens the paradigm of Cross-Kingdom RNA communication! Big congrats to @J_NinoSanchez, @HuaitongW and all! Thanks for your hard work! cell.com/molecular-plant/abs…
Our new discovery that bacteria utilize extracellular vesicles to deliver RNAs into fungi substantially broadens the paradigm of Cross-Kingdom RNA communication! Big congrats to @J_NinoSanchez, @HuaitongW and all! Thanks for your hard work! cell.com/molecular-plant/abs…
Hailing Jin retweeted
SWBio DTP PhD (Univ Exeter): Will global warming speed up antifungal resistance? Work with Profs Gabriel Yvon-Durocher, & Neil Gow & team. Experimental evolution, multiomics & modelling on medical/crop pathogens. Apply: bpb-eu-w2.wpmucdn.com/blogs.… #PhD #AMR #ClimateChange #Mycology
Truly grateful to Vanderbilt EV Center Director Alissa Weaver for bringing us together and organizing such an inspiring event. Very excited to see you, Brian, and all the EV experts, and learned so many exciting EV stories!
A truly inspiring visit to the @VU_EVresearch annual retreat. Many thanks to Alissa Weaver co-chair of the 2024 @AAEV_org for the invitation. Enjoyed the panel with @hailingj1 and Brain Eliceiri.
Hailing Jin retweeted
Science delivers medicines, clean air and water, safe food, and smarter choices—saving billions of lives. Proposed cuts to @NIH and @NSF would shutter labs, stall new cures, hurt our economy, and send future scientists elsewhere. Hear from patients saved by science: tinyurl.com/m65339fh. To share your story of how #ScienceSavedMe, email [email protected].
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Great work and must read! It’s extremely useful to the plant community!
Tremendous work by the extremely talented postdocs! @TrALEE_Sci @NatanellaE @nobolly .Thank you for putting in a major effort on this “side project” to develop a power community resource arabidopsisdevatlas.salk.edu…
Hailing Jin retweeted
Former students and colleagues of Dr. John McDowell published a @MPMIjournal article detailing John's amazing scientific achievements in the field of molecular plant-microbe interactions. John was a dedicated mentor, teacher, and friend to many within and beyond Virginia Tech.
Hailing Jin retweeted
Cross-kingdom RNAi is everywhere:
🍅 Pathogens use sRNAs to suppress plant immunity
🌱 Symbionts use sRNAs to promote compatibility
🦟 Even mosquitoes aren’t safe
Hailing Jin @hailingj1 at #ISMPMI2025: revealing how small RNAs cross borders—and shift the balance.
#CKRNAi
Hailing Jin retweeted
Our latest made to the cover @ScienceAdvances! The power of chemistry unveiled the signal specificity boundary bet/w development & immunity.
Congrats, Arvid, Krishna @mohansepuri , Pengfei, all the collaborators, esp. @Itamilab 🥳⚗️🌱.
science.org/doi/10.1126/scia…
Congratulations again🎉🎉🎉
Finalising the move from #Vienna to #Heidelberg Lesson’s at my office &🚪 @gmivienna that kept me company. 🧵 1/ Advice from my daughters
#RNATx2025 Victor Ambros, 2024 Nobel Laureate, elegantly elucidated the complex lin4-LIN14, let7-LIN28 and Lep5 regulatory network in C. elegant development. He emphasized the importance of conditionality and redundancy in miRNA-mediated regulation - which often overlooked!
Hailing Jin retweeted
Gene editing pioneer @davidrliu discusses baby K.J. Muldoon, the first person treated with a customized gene editing therapy, what made K.J.'s treatment possible, and how on-demand treatments for rare genetic diseases could one day become routine. broad.io/DLQA




































