Jay Detsky (@jaydetsky) header
Jay Detsky (@jaydetsky) profile picture

Staff Radiation Oncologist @sunnybrook treating CNS and GU tumors; Assistant Professor @UofTDRO; https://nitter.cf/t.co/5hMkgotcUb

Toronto, ON
Joined August 2010
Photo by Jay Detsky (@jaydetsky)Photo by Jay Detsky (@jaydetsky)Photo by Jay Detsky (@jaydetsky)Photo by Jay Detsky (@jaydetsky)Photo by Jay Detsky (@jaydetsky)Photo by Jay Detsky (@jaydetsky)Photo by Jay Detsky (@jaydetsky)Photo by Jay Detsky (@jaydetsky)Photo by Jay Detsky (@jaydetsky)Photo by Jay Detsky (@jaydetsky)
Jay Detsky retweeted
Replying to @jaydetsky
@jaydetsky from @Sunnybrook presenting the award winning data from the UNITED trial. #MRlinac adaption improves coverage and decreases normal brain exposure in #GBM patients recieving #radiotherapy #mrlinacconsortium
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Great first session @mr_linac #mrlinacconsortium including exciting data from @Sunnybrook @jaydetsky doing great work to improve outcomes in GBM
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Understand the magnitude of what those Israeli passengers may have just prevented. If the emerging reports are correct, an Omani pilot attempted to deliberately crash a passenger jet carrying roughly 180 people from Dubai to Tel Aviv, sending the aircraft into a terrifying plunge before Israelis on board overpowered and subdued him. Had that plane gone down, regardless of where it crashed, this would not simply have been another aviation disaster. It would have been a 9/11-scale terrorist attack involving an Emirati aircraft, Israeli civilians, an Omani pilot, Saudi airspace, and a region already engulfed in conflict. Think about the military response that would have followed. Think about the countries that would have been dragged in. Think about the retaliatory chain reaction that would have been set in motion. The consequences are genuinely impossible to calculate, but they would have been cataclysmic. The Israelis who bravely took control of that situation did not merely save the lives of the people sitting beside them. They may have prevented an event that would have rewritten the history of the Middle East, reverberated across the world, and cost an unimaginable number of lives. There are moments when ordinary people, in the span of a few terrifying minutes, stand between the world as it is and a world permanently changed by catastrophe. This may have been one of them.
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I find this @JCO_ASCO article rather puzzling. I treat glioblastoma routinely, and the premise that we are routinely giving prophylactic dexamethasone simply does not reflect contemporary neuro-oncology practice - at least not any practice I’m familiar with. We use steroids when patients are symptomatic from tumor- or treatment-related edema, usually for the shortest period necessary, because they can produce rapid and sometimes dramatic symptomatic improvement. Of course we recognize the toxicities and taper aggressively when clinically feasible. The emphasis on infection-related morbidity also feels overstated relative to my clinical experience. Significant infectious complications from short-term dexamethasone are uncommon, and many of us increasingly use steroid-sparing approaches, including Boswellia, when appropriate. Most puzzling is presenting bevacizumab as a preferable steroid-sparing strategy. Bevacizumab is hardly benign: it carries meaningful toxicity, requires IV infusions and monitoring, and imposes its own burden on patients and quality of life. Steroids should absolutely be used judiciously. But arguing against a version of clinical practice that many of us don't actually practice, and then proposing bevacizumab as the safer alternative - makes for a very odd article.
Corticosteroids in Glioblastoma Management: A Reconsideration of a 65-Year Practice. Read the full article. bit.ly/4wvCiyy
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Jay Detsky, MD, PhD, discusses phase 2 #UNITED results evaluating MRI-guided adaptive radiotherapy for newly diagnosed #glioblastoma. Learn more: hmpgloballearningnetwork.com…
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Congrats to Drs. Meredith Giuliani and Alex Louie on their 2026 @ASTRO_org honours!🎉Dr. Giuliani received the ASTRO Mentorship Award, and Dr. Louie was named a Fellow of ASTRO (FASTRO). Well deserved! uoft.me/utdro-astro2026-MG-A…
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Jay Detsky retweeted
New findings in glioblastoma show how MR‑guided adaptive radiotherapy can reduce treatment volumes by 40% while maintaining outcomes and a 4% marginal failure vs 11% historically. A step forward in delivering precise care and helping protect healthy brain tissue. 👉 Read the full study in The Lancet Oncology: bit.ly/4tLKIzT *Study by Detsky et al., UNITED trial investigators at Sunnybrook Health Sciences Centre.
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Replying to @Sunnybrook
@Sunnybrook is having a pretty good weekend. Here is a nice secondary analysis of UNITED just presented at ESTRO 2026 and published in Green journal. Suggests FLAIR chasing does nit impact margin failure rates. @jaydetsky @SahgalArjun “Influence of FLAIR inclusion on patterns-of-failure and outcomes in glioblastoma: results from the UNITED prospective adaptive radiotherapy trial - Radiotherapy and Oncology” thegreenjournal.com/article/…
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Jay Detsky retweeted
Great way to start the day with our @Sunnybrook @UofTDRO resident appreciation breakfast. We are so lucky to have such talented and kind residents caring for our patients.
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Registrations are open for our next Consortium Knowledge Exchange webinar on the UNITED Trial with Dr. Jay Detsky from Sunnybrook Hospital, Canada. Register on the MR-Linac Consortium Member Portal today!
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"Universities shape climate. Leadership is not measured by how quickly a slide is removed; it measured by whether you understand why it never should have been there in the first place" | @MatthewTaub @_UJewishOrg @KishenAnil does not belong as dean @UofTDentistry cc: @UofT
I'd like to hear how @KishenAnil defends this failure in judgment and leadership. Indeed, is RCDSO comfortable with his exploitation of the power differential, in violation of its Standards of Practice? @UofTDentistry @UofT
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There should be applause for competent investigators, not disingenuous instigators. This paper adds nothing that we didn't already know, but instead falsely frames the minority subset of patients with serious adverse events as a majority event.
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A huge pleasure and honor to present in beautiful Israel. Thank you for your hospitality! #hope #HCC #SBRT
Truly an honor to have Dr Laura Dawson (past @ASTRO_org President!) speak at the Second Annual Radiation Oncology conference in @Israel today Her pioneering work on #radonc for liver cancers is truly remarkable @ldawsonmd @eli_sapir
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Jay Detsky retweeted
If you guessed 40–70%, you're right! Want to learn more about this breakthrough in high-grade glioma treatment? Tune in to hear @SahgalArjun on the latest episode of our podcast, Spilling the RT ➡️ bit.ly/4jSo4BD
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You can’t take our country — and you can’t take our game.
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What a privilege to give grand rounds at @MSKCancerCenter and share our @Sunnybrook @Elekta @MRLinac @jaydetsky UNITED #glioblastoma experience. We continue to shape the future of radiation for #GBM through volume and dose reduction using online real-time MR guided radiation.
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The amazing @UofTDRO @Sunnybrook #superstar fellow @DMoorePalhares giving his award winning talk on monitoring radiologic biomarkers of response in GBM patients at the @mr_linac annual meeting
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Jay Detsky retweeted
At #ASTRO24 @Xristodouleas caught up with UNITED trial PI @jaydetsky on how @Sunnybrook researchers were able to significantly reduce radiation exposure to healthy 🧠 using Unity. Tune in to hear the difference in treatment volumes at Sunnybrook vs the historical standard. #MRgRT
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UNITED Trial Demonstrates Major Advancement in Radiation Therapy of High-Grade Gliomas at #ASTRO24 🔗 bit.ly/3Bukg8k “MR-guided adaptive radiation may represent the first major advance in radiation treatment for high-grade gliomas in over 25 years” #RadOncNews
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