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Kwok Lab

@kitkwok6

G-quadruplex, RNA structures and interactions, RNA epigenetics, Gene regulation, Aptamers

 Hong Kong
kitkwok.com
Joined April 2015
  • Tweets2.1K
  • Following261
  • Followers1.8K
174Media
Photo by Kwok Lab (@kitkwok6)Photo by Kwok Lab (@kitkwok6)Photo by Kwok Lab (@kitkwok6)Photo by Kwok Lab (@kitkwok6)Photo by Kwok Lab (@kitkwok6)Photo by Kwok Lab (@kitkwok6)Photo by Kwok Lab (@kitkwok6)Photo by Kwok Lab (@kitkwok6)Photo by Kwok Lab (@kitkwok6)Photo by Kwok Lab (@kitkwok6)
Please RETWEET! 2 postdocs (one chemical biologist, one RNA biologist) and multiple PhD positions are available at #KwokLab, City University of Hong Kong. We work on #RNA, #Gquadruplex, #aptamer , #peptide, #Biosensor and more! See kitkwok.com . PM if interested.
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Celebrating Caroline on her collaborative paper now published in Genome Biology! doi.org/10.1186/s13059-026-0…
Image from Kwok Lab (@kitkwok6)
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A new #KwokLab collaboration paper has been released in Genome Biology: "Landscape and mutational dynamics of G-quadruplexes across the complete human genome." Congrats to the authors ! 🎉 doi.org/10.1186/s13059-026-0… @CityUHongKong @CityUScience @CityUChem @GenomeBiology
Landscape and mutational dynamics of G-quadruplexes across the complete human genome

Landscape and mutational dynamics of G-quadruplexes across the complete human genome

Genome Biology - G-quadruplexes (G4s) are alternative DNA structures with diverse biological roles, but their examination in highly repetitive parts of the human genome has been hindered by the...

link.springer.com
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BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2026 #NobelPrize in Physics to Francis Halzen “for decisive contributions to the IceCube Neutrino Observatory and the discovery of high-energy neutrinos of astrophysical origin.”
Image from The Nobel Prize (@NobelPrize)
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BREAKING NEWS The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
Image from The Nobel Prize (@NobelPrize)
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Kwok Lab retweeted
HKRNAClub (@HKRNAClub) profile picture
HKRNAClub@HKRNAClubOct 2
#HKRNAClub Oct hybrid seminar is coming! We are honored to have Prof. Tuan Anh Nguyen from Hong Kong University of Science and Technology to present the structural and functional dynamics of DICER. Registration required: cityu.zoom.us/meeting/regist… @RNASociety @lexogen
Image from HKRNAClub (@HKRNAClub)
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新しいレビュー論文が公開されました！ context依存的に翻訳を制御するさまざまな化合物についてまとめています。 nature.com/articles/s41589-0…
Halting translation by the letter with sequence-selective small molecules

Halting translation by the letter with sequence-selective small molecules

Nature Chemical Biology - Small-molecule modulators of protein synthesis are invaluable tools for dissecting the translation apparatus. This Review summarizes the mechanisms of molecules that...

nature.com
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What an exciting few days in Hong Kong! I had the honour of speaking at the Hong Kong RNA Club Seminar Series at City University of Hong Kong, where I shared our work on chemically synthesized mRNA Huge thanks to Prof. Chun Kit Kwok for the kind invitation and the warm hospitality — great science, a memorable dim sum lunch with his lab, and even a face-off with Bruce Lee at Victoria Harbour. #RNA #mRNA #HongKong #CityUHK #NagoyaUniversity
Image from Hiroshi Abe (@Gaussian55You)
Image from Hiroshi Abe (@Gaussian55You)
Image from Hiroshi Abe (@Gaussian55You)
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Kwok Lab retweeted
HKRNAClub (@HKRNAClub) profile picture
HKRNAClub@HKRNAClubSep 18
Thanks Prof. Prof. Hiroshi Abe @Gaussian55You from Nagoya University for sharing his work on chemistry-based mRNA design enhancing translation toward therapeutics in @HKRNAClub hybrid seminar! Over 90 participants attended! #HKRNAClub #RNA @RNASociety @lexogen
Image from HKRNAClub (@HKRNAClub)
Image from HKRNAClub (@HKRNAClub)
Image from HKRNAClub (@HKRNAClub)
Image from HKRNAClub (@HKRNAClub)
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Kwok Lab retweeted
HKRNAClub (@HKRNAClub) profile picture
HKRNAClub@HKRNAClubSep 14
Don't miss our #HKRNAClub hybrid seminar on 17 Sep at HKT 4:30 pm! Refreshments will be provided, we hope to see all of you there! Registration required: cityu.zoom.us/meeting/regist… @CityUHongKong @CityUScience @CityUChem @RNASociety @lexogen
Image from HKRNAClub (@HKRNAClub)
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Honored to speak at the @HKRNAClub Seminar (City University of Hong Kong) on 17 Sep 2026! Sharing our lab's chemistry-based mRNA design for enhanced translation & RNA therapeutics. Hybrid — join in person or on Zoom; details in the poster. Thanks, Prof. Kwok! #RNA #mRNA
Image from Hiroshi Abe (@Gaussian55You)
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RNA molecules perform remarkably diverse roles in biology. Accurately predicting RNA structure from sequence promises to accelerate understanding of RNA mechanisms and the design of synthetic RNA medicines and devices. However, RNA structure prediction has proven to be a formidable problem. In a new Science study, researchers report an important assessment of state-of-the-art deep learning methods developed toward this goal. Learn more in a new #SciencePerspective: scim.ag/4h3lr0J
Image from Science Magazine (@ScienceMagazine)
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Kwok Lab retweeted
HKRNAClub (@HKRNAClub) profile picture
HKRNAClub@HKRNAClubAug 17
#HKRNAClub Sep hybrid seminar is coming! We are honored to have Prof. Hiroshi Abe @Gaussian55You from Nagoya University to present chemistry-based mRNA design enhancing translation toward therapeutics. Registration required: cityu.zoom.us/meeting/regist… @RNASociety @lexogen
Image from HKRNAClub (@HKRNAClub)
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Kwok Lab retweeted
Cell (@CellCellPress) profile picture
Cell@CellCellPressAug 13
Now online! Functional atlas of vertebrate viral RNA elements that stabilize RNA and enhance translation dlvr.it/TV0bwF
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Kwok Lab retweeted
HKRNAClub (@HKRNAClub) profile picture
HKRNAClub@HKRNAClubAug 13
Thanks Prof. Ling-Ling Chen from Shanghai Institute of Biochemistry and Cell Biology for sharing her work on linking RNA processing & function, and beyond in @HKRNAClub hybrid seminar! Over 80 online and on-site participants attended! #HKRNAClub #RNA @RNASociety @lexogen
Image from HKRNAClub (@HKRNAClub)
Image from HKRNAClub (@HKRNAClub)
Image from HKRNAClub (@HKRNAClub)
Image from HKRNAClub (@HKRNAClub)
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Kwok Lab retweeted
HKRNAClub (@HKRNAClub) profile picture
HKRNAClub@HKRNAClubAug 11
Don't miss our #HKRNAClub hybrid seminar on 12 Aug at HKT 4:30 pm! Refreshments will be provided, we hope to see all of you there! Registration required: cityu.zoom.us/meeting/regist… @CityUHongKong @CityUScience @CityUChem @RNASociety @lexogen
Image from HKRNAClub (@HKRNAClub)
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New #KwokLab collaboration paper to be published in NAR! "RNA G-quadruplex structure recognition by chimeric peptides." Congrats to the authors!!👏 doi.org/10.1093/nar/gkag745 @CityUHongKong @CityUScience @CityUChem
RNA G-quadruplex structure recognition by chimeric peptides

RNA G-quadruplex structure recognition by chimeric peptides

Abstract. G-quadruplexes (G4s) are non-canonical nucleic acids involved in gene regulation and have attracted interest as potential therapeutic targets. Ho

academic.oup.com
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Thrilled to share the latest review I had the incredible pleasure to write together with @TonyMustoe, out today in #COSB, about probing #RNA structural ensembles, non-equilibrium intermediates and isoforms. Check it out: sciencedirect.com/science/ar…
Image from Danny IncaRNAto (@incaRNAtolab)
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Kwok Lab retweeted
HKRNAClub (@HKRNAClub) profile picture
HKRNAClub@HKRNAClubJul 15
#HKRNAClub Aug hybrid seminar is coming! We are honored to have Prof. Ling-Ling Chen from Shanghai Institute of Biochemistry and Cell Biology to present linking RNA processing & function, and beyond. Registration required: cityu.zoom.us/meeting/regist… @RNASociety @lexogen
Image from HKRNAClub (@HKRNAClub)
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Excited to share our new preprint: Structural assemblies for an RNA world. We show that short RNAs can self-assemble into protein-like architectures, including closed cages, finite oligomers, and filaments. biorxiv.org/content/10.64898…
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Kwok Lab retweeted
HKRNAClub (@HKRNAClub) profile picture
HKRNAClub@HKRNAClubJun 12
Thanks Prof. Polly Leilei Chen @Pollych34650771 from National University of Singapore to present dsRNA pathways and their role in immune evasion in @HKRNAClub hybrid seminar! Over 60 online and on-site participants attended! #HKRNAClub #RNA @RNASociety @lexogen
Image from HKRNAClub (@HKRNAClub)
Image from HKRNAClub (@HKRNAClub)
Image from HKRNAClub (@HKRNAClub)
Image from HKRNAClub (@HKRNAClub)
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