Pratyusha Duvvuri (@pratduvvuri) profile picture

Stealth repeat founder. SPC, Galileo (acq. Cisco), Meta, Apple, Two Sigma. CMU.

Joined September 2026
Photo by Pratyusha Duvvuri (@pratduvvuri)Photo by Pratyusha Duvvuri (@pratduvvuri)Photo by Pratyusha Duvvuri (@pratduvvuri)Photo by Pratyusha Duvvuri (@pratduvvuri)Photo by Pratyusha Duvvuri (@pratduvvuri)Photo by Pratyusha Duvvuri (@pratduvvuri)Photo by Pratyusha Duvvuri (@pratduvvuri)Photo by Pratyusha Duvvuri (@pratduvvuri)Photo by Pratyusha Duvvuri (@pratduvvuri)Photo by Pratyusha Duvvuri (@pratduvvuri)
In college, I ran my own startup. MULTIPLE investors wanted me to drop out. I said no. I wanted my college experience, my degree, and I couldn’t see myself spending five years on that particular idea. Years later, I’ve left my $$$ job to go all in on founding. I’d been itching to do this for a while. After @Cisco acquired Galileo, I promised to help my comrades get one last ambitious project to general availability. We shipped it, and I kept my promise :)) Still, leaving felt very bittersweet. Spent 1.5 years at Galileo with my partners in crime, then five months building alongside new teammates at @splunk + @Cisco post acquisition. I’m now looking for co-founders 😁 I’ve built AI infrastructure, observability and tokenomics at Galileo, launched portfolios as a quant engineer at Two Sigma, and worked directly with enterprise customers. I LOVE to figure out what’s worth building, lead the product + technical work, and get v v hands-on to ship it. I’m really interested in meeting people who know a problem deeply and want to build a company around solving it. If that’s you, or someone you think I should meet, let’s talk! Comment on the post/ DM me. ⚡️ pratyushaduvvuri.com ⚡️
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Pratyusha Duvvuri retweeted
OpenAI's computer-using agents can now operate almost any app the way a person does, clicking and typing through software that never got an API, and the team building them says they're close to beating expert humans on speed. Ari Weinstein works on OpenAI's consumer computer use products, and James Sun works on the enterprise side. Both were startup founders before joining OpenAI. They join a16z's Seema Amble and Fabrizio Serafini to discuss what OpenAI's Astra model changed for computer use, the controls enterprises need for agents they can no longer watch, why computer use works as a universal API for legacy ERPs and finance systems, and why they think cheap software will push UI to get better and more personal. 0:50 What Astra changed for computer use 3:23 Consumer vs. enterprise computer use 5:43 How James runs his workday with Dots 8:06 When computer use becomes superhuman 10:01 How much autonomy to give agents 11:36 What agents mean for ad-supported sites 13:51 Computer use as the universal API 17:21 Getting enterprises to trust agents 20:22 Why the best use cases are the boring ones 25:37 Why UI isn't going away 32:38 Advice for founders building on agents 37:31 Making computer use feel coherent 40:57 Computer use's scaling moment YouTube: youtu.be/9v42ZOdiBJY @AriX @JamesZmSun @OpenAI @seema_amble @fabserafini
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“Faster than the average human” makes a headline. @a16z @OpenAI, which tasks, which humans, and at what success rate? 👀 For back-office work, show me cost per correctly completed task against VAs hired at these published rates 🇵🇭 Philippines $6-9/hr 🇮🇳 India $5-8/hr 🇰🇪 Kenya $6-15/hr For the same work, same quality bar... let's count retries, corrections and human supervision on both sides. Beating human speed doesn’t settle the unit economics.
OpenAI's computer-using agents can now operate almost any app the way a person does, clicking and typing through software that never got an API, and the team building them says they're close to beating expert humans on speed. Ari Weinstein works on OpenAI's consumer computer use products, and James Sun works on the enterprise side. Both were startup founders before joining OpenAI. They join a16z's Seema Amble and Fabrizio Serafini to discuss what OpenAI's Astra model changed for computer use, the controls enterprises need for agents they can no longer watch, why computer use works as a universal API for legacy ERPs and finance systems, and why they think cheap software will push UI to get better and more personal. 0:50 What Astra changed for computer use 3:23 Consumer vs. enterprise computer use 5:43 How James runs his workday with Dots 8:06 When computer use becomes superhuman 10:01 How much autonomy to give agents 11:36 What agents mean for ad-supported sites 13:51 Computer use as the universal API 17:21 Getting enterprises to trust agents 20:22 Why the best use cases are the boring ones 25:37 Why UI isn't going away 32:38 Advice for founders building on agents 37:31 Making computer use feel coherent 40:57 Computer use's scaling moment YouTube: youtu.be/9v42ZOdiBJY @AriX @JamesZmSun @OpenAI @seema_amble @fabserafini
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Jokes aside, respect to @tomekkorbak and @balesni for helping outside researchers investigate the Hugging Face incident 🫡 mad respect
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fewer safety escalations sounds great until you check what stopped reaching the humans. @GenReasoning found this in Avalon's safety simulations. agents kept refusing harmful actions but reported safety concerns to humans less as training progressed. so fewer escalations alone isn't a safety win. measure the concerns that should've reached a human and didn't.
Introducing Reinforcement Learning from Collective Rewards (RLCR). RLCR is a recipe that trains language models as agent organisations, which share a message board and workspace. We use it to train Avalon-M1-Mini (120B) and study its behaviour. We find a number of interesting results, including: 🛠️ Learnt organisational hierarchies and divisions of labour 🕵️ Increased collective verification, through hires of verifiers and testers 👥 The rise of collective thinking, where agents think more about other agents and how to help them We believe RLCR can provide a laboratory for studying collective intelligence and multi-agent safety. Blog post and technical report 👇
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Updating WordPress or your plugins won’t fix this. The vulnerability is in PHP itself and can let attackers run code without logging in. Ask your host to confirm the PHP security patch is deployed and the affected workers have restarted. If you manage it yourself, update every PHP runtime and verify the patched version is actually running. Web Application Firewall rules can buy time, but they don’t replace the patch. @official_php
OpenAI models helped researchers—operating as part of our Patch the Planet initiative—discover critical security flaws in PHP, an open-source programming language used to run an estimated 70% of websites. Over the past two months, we led a coalition of maintainers, researchers, and security providers to prepare fixes and protections ahead of disclosure. This duration was necessary because the fix was quite intricate and required a major change to the PHP engine. Every site using PHP can now safely upgrade their version to stay secure, in addition to applying mitigations from various security vendors. Due to the severity of these flaws and PHP’s widespread use, we consider this bug to be one of the most impactful vulnerabilities in recent memory. It also marks a new phase, where AI can find security bugs with internet-scale impact. This is an example of the Defender’s Window in action: to our knowledge, frontier AI was able to find this vulnerability ahead of attackers, giving defenders time to prepare. openai.com/index/coordinated…
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Your AI agent can chase the wrong amount even when your company already has the information to correct it. I’m exploring AI for finance teams, and these gaps between what a business knows and what its software acts on are gnarly :'). Here are three situations I've seen repeatedly across conversations w/ financial controllers and credit teams. 1. A customer returns goods, but the supplier’s accounts still show the full bill. One controller described returns taking three or six months to get recorded. Finance can end up chasing an overstated balance, then spending time untangling the dispute. The worst part - automating reminders without reconciling the return repeats the wrong alerts. 2. A supplier delivers equipment, but the buyer can’t process payment. Often times this is because installation isn't done, or the acceptance documents haven't arrived in the buyer's inbox yet. Someone needs to identify the missing requirement and get it completed. 3. An agent prepares a supplier payment correctly. But preparing it and authorizing it are separate jobs. If the workflow requires a person’s approval, the agent needs to stop there, even if every number is right. It's hard to bake in that control in all scenarios. I see a burning opportunity rn for AI to match returned goods to the right invoices, identify missing payment documents and route the work to whoever can resolve it, with controls baked in.
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China’s MiniMax was hiding behind a bunny. Space Bunny is M3.1 Flash 🐰!! Only 0.60 for a million output tokens, down from M3’s $1.20 standard rate. Weights are gonna be out October 23. Guess I know what I’m testing this weekend :P
MiniMax M3.1 Flash: Space Performance + Bunny Speed 🚀🐰 Yes, Space Bunny - which has topped global leaderboards with 200T+ tokens - was an earlier version of M3.1 Flash. 💰Redefining the performance economics of agentic AI. M3.1 Flash achieves frontier-level intelligence across key tasks such as Cowork (Automation-Bench: 62%; ALE: 30%), Coding (DeepSWE: 74%) and Visual Reasoning (BabyVision: 91%), at 1/3 the cost of M3 and 3x the speed. API pricing (flat rate): $0.15 / $0.60 per 1M input/output tokens, with cache reads at $0.015 / 1M tokens. Model weights will arrive on Oct 23. API: platform.minimax.io M Plan: minimax.io/m-plan MiniMax Code for desktop: agent.minimax.io/download
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You Can See Everything was a rollercoaster. I caught myself thinking - Is Elizabeth Holmes actually innocent? Is she just naive? I could feel her reality distortion field working on me. I tried to watch @nathanfielder and Lance Oppenheim’s documentary with as little of what I already knew about Holmes in my head as possible. Spoilers below. Walking out, my friend said the extreeeemly intimate setting was what made the film so good. It’s so rare to see someone at the center of an enormous corporate fraud in this setting: inside her family, in ordinary conversations, with the people who love her. I agree. In that setting, I found myself entertaining explanations I wouldn’t have expected to. Was she unintentionally misleading people? Did she believe what she was saying? Did she understand how other people would hear it? The conversation about what Theranos’s machines “can” do captures that confusion. Is she describing something that works now, or something that could be made capable of working? That difference matters enormously when you’re telling people what a blood-testing device can do. But listening to her explanation, I could feel myself trying to work out how she understood her own words. On the other hand, I think the score was nudging the audience toward suspicion. I could feel it changing how I interpreted what was happening on screen. Nathan plays “Who’s on First?”, an old comedy routine where two people interpret the same words differently, to illustrate how confusing he finds their conversation. Watching Holmes react, with that suspicious music underneath, I felt myself looking for something sinister. I’d love to watch that scene again with just their voices and the room around them. Would I read her reaction the same way? That was the strange experience of this film for me. I could feel myself being pulled into Holmes’s version of events, while also noticing how the filmmaking was pulling me toward suspicion. The film gives us reasons to question Nathan’s perspective too. So yes, getting to see these ppl up close made me want to understand them more. It also made me much less certain I could... #YouCanSeeEverything
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My husband is learning Hindi. I learned it as a kid, so my feedback is basically “sounds right” or “sounds wrong.” Told him “I can be your verifier, man. you gotta do the gradient descent yourself."
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With all the conversation around @nickcammarata’s interpretability essay, I hope this quantum computing paper doesn’t get lost. I think it deserves attention too! Researchers at @Harvard and @AnthropicAI just published work using Claude to design better quantum circuits, the sequences of operations a quantum computer uses to carry out a calculation. 1. Claude reduced both memory requirements and computation across seven of eight tasks. Quantum computers store information in qubits and manipulate it through operations called gates. Some gates are much more expensive to implement than others. This paper counts Toffoli gates, a costly operation commonly used to measure the work a quantum algorithm requires. Across seven of eight tasks, the researchers report improvements in both qubit and Toffoli counts over the published designs they compared against. For one decoding routine, the expensive gate count fell from 5.1 million to 440,000, about a 12x reduction, while qubit requirements fell by 5.2%. These are resource estimates, not measured hardware speedups. Still, that’s a substantial improvement :)) These routines are building blocks for larger quantum algorithms. Reducing their resource requirements could make those algorithms feasible on smaller machines or with less computation. And one of their results goes beyond reducing operation counts. 2. It found a way to recover earlier decisions without storing the full history. These quantum computations need to be reversible. Temporary information can’t simply be discarded as it would be in ordinary software; it has to be cleared without disturbing the result. Lemme explain. Imagine an algorithm that repeatedly chooses between several steps. To undo those steps, a straightforward implementation keeps a log of its choices. That log can require a lot of extra qubits. Claude derived mathematical relationships that let the circuit reconstruct earlier choices from the numbers it already held. That made a classical arithmetic method called divsteps viable for reversible quantum arithmetic, with new trade-offs between memory and computation. 3. The search combined automated tests with mathematical verification. Researchers supplied the task and an evaluator. Claude explored different designs, received correctness feedback and resource scores, and revised them. Early attempts at reconstructing those choices passed small tests but failed on 256-bit inputs. The eventual approach used mathematical derivations, numerical tests, and a branch-recovery claim formalized in Lean, a proof-checking system. BTW, this part is also connected to Nick’s essay. He describes agents explaining what neurons respond to, then testing predictions from those explanations. Both put proposed ideas up against evidence, though the tests establish different things. I’m excited about models contributing ideas this specific, with tests and mathematical checks we can inspect. If we can extend that to more research problems, there’s a lot to look forward to.
LLMs have gotten very good at making classical code do more with less, from faster CUDA kernels to leaner compilers. This summer, as part of the Anthropic STEM Fellows program, we asked whether Claude could do the same for quantum computers. We found it can. Across a wide range of tasks, Claude's circuits need fewer qubits and less running time than the best published designs. The video shows the most striking one: modular inversion, the costliest step in the quantum algorithm for elliptic-curve discrete log. Claude built it on a classical method few thought could work on quantum computers.
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Your team’s AI bill doubled 🫠. Is that wasted spend, or money well spent? Before you can answer, you need to know where the increase came from. More people using AI? A few heavy users? Unnecessary Opus 5.5 and Astra 6 use? At Galileo (acquired by @Cisco) and now @splunk agent observability, we were piecing that story together across five AI providers, each with its own definition of usage. Here's another qs - Whose budget does that usage belong to? Knowing someone’s manager doesn’t automatically give you the answer. In fact, finance may attribute your manager's spend to a different category than your spend... We’ve been building tokenomics in Splunk Agent Observability to help employees understand their usage, managers understand adoption, and finance connect spend to budgets. That gives people a starting point for deciding whether the spend makes sense :). We learned A LOT building the tokenomics product for CRAZY different ICPs - Engineers, Finance folks and Management ..... all while building it for the scale of a 100K ppl at Cisco - our first customer. I wrote all about in my blog (in 🧵), please tell us what you'd wanna see in a product like this. what does tokenomics mean to you?
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