Renée T. (@rrenee_t) profile picture
Joined July 2024
An overview of the blood brain barrier and drug transport in health and disease @CellRepMed sciencedirect.com/science/ar…
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Vagus Nerve Signals Regulating Heart Function Discovered Researchers have successfully isolated individual neurons in the vagus nerve that are responsible for regulating cardiovascular function in humans. By identifying neurons that fire in sync with the heartbeat, they were able to distinguish those that monitor heart function from those that control heart rate. This breakthrough allows scientists to study how vagus nerve activity changes in cardiovascular disease. Previous research on the vagus nerve relied mostly on animal models, but this study provides the first direct insights from human participants. The findings could lead to new treatments by targeting specific neurons involved in heart regulation. Future research will investigate how these neurons behave in individuals with cardiovascular disease.
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Simplified view of metabolism. Proteoforms & metabolites are abstracted. Many of the parameters are unknown. Regulatory links are missing.
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New studies from our lab published in @CellChemBiol designing anti-diabetic metabolic routes using novel small molecules (SR-18292) that re-direct lactate and gluconeogenic carbon substrates to mitochondrial oxidation cell.com/cell-chemical-biolo…
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Thrilled to announce that my back-to-back co-first author papers are out today in @Nature! We present a long-term clinical study in patients and a preclinical study in mice, demonstrating the unexpected role of type-2 immunity in sustaining durable CAR T and ICB immunotherapies!
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Researchers @HeartCare4Kids and @PennCVI demonstrate that powerful #SGLT2 inhibitors act independently of SGLT2 to benefit #HeartFailure. . Learn more at ahajrnls.org/3yQKAsv
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